Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10694.145 | 0.0054 | -0.7988 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14158.189 | 0.9871 | 0.9855 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14158.189 | 0.9871 | 0.9855 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14158.189 | 0.9684 | 0.9643 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14158.189 | 0.9684 | 0.9643 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14158.189 | 0.9830 | 0.9809 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14158.189 | 0.9830 | 0.9809 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14158.189 | 0.9564 | 0.9506 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14158.189 | 0.9564 | 0.9506 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14158.189 | 0.9572 | 0.9515 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14158.189 | 0.9572 | 0.9515 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14158.189 | 0.0810 | -0.5114 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14158.189 | 0.0810 | -0.5114 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14158.189 | 0.0034 | -0.9176 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14158.189 | 0.0034 | -0.9176 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14158.189 | 0.0069 | -0.8774 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14158.189 | 0.0069 | -0.8774 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14158.189 | 1.0463 | 1.0514 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14158.189 | 1.0463 | 1.0514 | 1.7834 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14260.189 | 1.0591 | 1.0736 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14260.189 | 1.0591 | 1.0736 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14260.189 | 1.0254 | 1.0318 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14260.189 | 1.0254 | 1.0318 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14260.189 | 1.0121 | 1.0152 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14260.189 | 1.0121 | 1.0152 | 1.5886 |