Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Methylglyoxal | 0.138 | uM | 13611.184 | 0.9170 | 0.8043 | 0.8419 | |||
| MDA-MB-157 | TNBC | Basal B | Methylglyoxal | 0.691 | uM | 13611.184 | 0.9347 | 0.8458 | 0.8419 | |||
| MDA-MB-157 | TNBC | Basal B | Methylglyoxal | 3.46 | uM | 13611.184 | 0.9086 | 0.7848 | 0.8419 | |||
| MDA-MB-157 | TNBC | Basal B | Methylglyoxal | 17.3 | uM | 13611.184 | 0.8904 | 0.7424 | 0.8419 | |||
| MDA-MB-157 | TNBC | Basal B | Methylglyoxal | 86.4 | uM | 13611.184 | 0.8733 | 0.7028 | 0.8419 | |||
| MDA-MB-157 | TNBC | Basal B | Methylglyoxal | 432 | uM | 13611.184 | 0.8038 | 0.5429 | 0.8419 | |||
| MDA-MB-157 | TNBC | Basal B | Methylglyoxal | 2160 | uM | 13611.184 | 0.1254 | -0.8301 | 0.8419 | |||
| MDA-MB-157 | TNBC | Basal B | Methylglyoxal | 10800 | uM | 13611.184 | 0.0198 | -0.9810 | 0.8419 | |||
| MDA-MB-157 | TNBC | Basal B | Methylglyoxal | 54000 | uM | 13611.184 | 0.1666 | -0.7621 | 0.8419 | |||
| MDA-MB-175-VII | HR+ | Luminal | Methylglyoxal | 0.138 | uM | 13676.184 | 0.9609 | 0.9166 | 0.9355 | |||
| MDA-MB-175-VII | HR+ | Luminal | Methylglyoxal | 0.691 | uM | 13676.184 | 0.9804 | 0.9580 | 0.9355 | |||
| MDA-MB-175-VII | HR+ | Luminal | Methylglyoxal | 3.46 | uM | 13676.184 | 0.9743 | 0.9450 | 0.9355 | |||
| MDA-MB-175-VII | HR+ | Luminal | Methylglyoxal | 17.3 | uM | 13676.184 | 0.9854 | 0.9688 | 0.9355 | |||
| MDA-MB-175-VII | HR+ | Luminal | Methylglyoxal | 86.4 | uM | 13676.184 | 0.9099 | 0.8079 | 0.9355 | |||
| MDA-MB-175-VII | HR+ | Luminal | Methylglyoxal | 432 | uM | 13676.184 | 0.9557 | 0.9054 | 0.9355 | |||
| MDA-MB-175-VII | HR+ | Luminal | Methylglyoxal | 2160 | uM | 13676.184 | 0.8055 | 0.5872 | 0.9355 | |||
| MDA-MB-175-VII | HR+ | Luminal | Methylglyoxal | 10800 | uM | 13676.184 | 0.1690 | -0.7009 | 0.9355 | |||
| MDA-MB-175-VII | HR+ | Luminal | Methylglyoxal | 54000 | uM | 13676.184 | 0.0051 | -0.9929 | 0.9355 | |||
| MDA-MB-361 | HER2amp | Luminal | Methylglyoxal | 0.138 | uM | 13516.184 | 1.0240 | 1.0860 | 0.5643 | |||
| MDA-MB-361 | HER2amp | Luminal | Methylglyoxal | 0.691 | uM | 13516.184 | 1.0243 | 1.0870 | 0.5643 | |||
| MDA-MB-361 | HER2amp | Luminal | Methylglyoxal | 3.46 | uM | 13516.184 | 1.0394 | 1.1418 | 0.5643 | |||
| MDA-MB-361 | HER2amp | Luminal | Methylglyoxal | 17.3 | uM | 13516.184 | 0.9687 | 0.8903 | 0.5643 | |||
| MDA-MB-361 | HER2amp | Luminal | Methylglyoxal | 86.4 | uM | 13516.184 | 0.9748 | 0.9115 | 0.5643 | |||
| MDA-MB-361 | HER2amp | Luminal | Methylglyoxal | 432 | uM | 13516.184 | 0.9578 | 0.8527 | 0.5643 | |||
| MDA-MB-361 | HER2amp | Luminal | Methylglyoxal | 2160 | uM | 13516.184 | 0.7324 | 0.1516 | 0.5643 |