Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | Methylglyoxal | 3.46 | uM | 13508.184 | 0.9928 | 0.9935 | 2.2235 | |||
| MCF12A | NM | Basal B | Methylglyoxal | 17.3 | uM | 13508.184 | 0.7929 | 0.8018 | 2.2235 | |||
| MCF12A | NM | Basal B | Methylglyoxal | 86.4 | uM | 13508.184 | 0.9604 | 0.9640 | 2.2235 | |||
| MCF12A | NM | Basal B | Methylglyoxal | 432 | uM | 13508.184 | 0.6665 | 0.6664 | 2.2235 | |||
| MCF12A | NM | Basal B | Methylglyoxal | 2160 | uM | 13508.184 | 0.0639 | -0.4193 | 2.2235 | |||
| MCF12A | NM | Basal B | Methylglyoxal | 10800 | uM | 13508.184 | 0.0120 | -0.7265 | 2.2235 | |||
| MCF12A | NM | Basal B | Methylglyoxal | 54000 | uM | 13508.184 | 0.0058 | -0.8032 | 2.2235 | |||
| MCF7 | HR+ | Luminal | Methylglyoxal | 0.138 | uM | 13555.184 | 1.0184 | 1.0345 | 1.0647 | |||
| MCF7 | HR+ | Luminal | Methylglyoxal | 0.691 | uM | 13555.184 | 1.0585 | 1.1097 | 1.0647 | |||
| MCF7 | HR+ | Luminal | Methylglyoxal | 3.46 | uM | 13555.184 | 1.0159 | 1.0298 | 1.0647 | |||
| MCF7 | HR+ | Luminal | Methylglyoxal | 17.3 | uM | 13555.184 | 0.9954 | 0.9913 | 1.0647 | |||
| MCF7 | HR+ | Luminal | Methylglyoxal | 86.4 | uM | 13555.184 | 1.0190 | 1.0357 | 1.0647 | |||
| MCF7 | HR+ | Luminal | Methylglyoxal | 432 | uM | 13555.184 | 0.9273 | 0.8631 | 1.0647 | |||
| MCF7 | HR+ | Luminal | Methylglyoxal | 2160 | uM | 13555.184 | 0.5116 | 0.0658 | 1.0647 | |||
| MCF7 | HR+ | Luminal | Methylglyoxal | 10800 | uM | 13555.184 | 0.0988 | -0.7725 | 1.0647 | |||
| MCF7 | HR+ | Luminal | Methylglyoxal | 54000 | uM | 13555.184 | 0.0086 | -0.9769 | 1.0647 | |||
| MDA-MB-134-VI | HR+ | Luminal | Methylglyoxal | 0.138 | uM | 13512.184 | 0.9379 | 0.9348 | 1.9355 | |||
| MDA-MB-134-VI | HR+ | Luminal | Methylglyoxal | 0.691 | uM | 13512.184 | 0.9252 | 0.9213 | 1.9355 | |||
| MDA-MB-134-VI | HR+ | Luminal | Methylglyoxal | 3.46 | uM | 13512.184 | 0.9651 | 0.9636 | 1.9355 | |||
| MDA-MB-134-VI | HR+ | Luminal | Methylglyoxal | 17.3 | uM | 13512.184 | 0.9496 | 0.9473 | 1.9355 | |||
| MDA-MB-134-VI | HR+ | Luminal | Methylglyoxal | 86.4 | uM | 13512.184 | 0.9730 | 0.9719 | 1.9355 | |||
| MDA-MB-134-VI | HR+ | Luminal | Methylglyoxal | 432 | uM | 13512.184 | 0.9152 | 0.9105 | 1.9355 | |||
| MDA-MB-134-VI | HR+ | Luminal | Methylglyoxal | 2160 | uM | 13512.184 | 0.6469 | 0.5969 | 1.9355 | |||
| MDA-MB-134-VI | HR+ | Luminal | Methylglyoxal | 10800 | uM | 13512.184 | 0.2009 | -0.1272 | 1.9355 | |||
| MDA-MB-134-VI | HR+ | Luminal | Methylglyoxal | 54000 | uM | 13512.184 | 0.0074 | -0.8420 | 1.9355 |