Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | Methylglyoxal | 86.4 | uM | 13639.184 | 0.9926 | 0.9907 | 1.5976 | |||
| LY2 | HR+ | Luminal | Methylglyoxal | 432 | uM | 13639.184 | 0.8673 | 0.8295 | 1.5976 | |||
| LY2 | HR+ | Luminal | Methylglyoxal | 2160 | uM | 13639.184 | 0.3604 | 0.0559 | 1.5976 | |||
| LY2 | HR+ | Luminal | Methylglyoxal | 10800 | uM | 13639.184 | 0.0200 | -0.8274 | 1.5976 | |||
| LY2 | HR+ | Luminal | Methylglyoxal | 54000 | uM | 13639.184 | 0.9971 | 0.9963 | 1.5976 | |||
| MCF 10A | NM | Basal B | Methylglyoxal | 0.138 | uM | 13551.184 | 0.9695 | 0.9796 | 3.0171 | |||
| MCF 10A | NM | Basal B | Methylglyoxal | 0.691 | uM | 13551.184 | 0.9528 | 0.9682 | 3.0171 | |||
| MCF 10A | NM | Basal B | Methylglyoxal | 3.46 | uM | 13551.184 | 0.9381 | 0.9581 | 3.0171 | |||
| MCF 10A | NM | Basal B | Methylglyoxal | 17.3 | uM | 13551.184 | 0.7499 | 0.8181 | 3.0171 | |||
| MCF 10A | NM | Basal B | Methylglyoxal | 86.4 | uM | 13551.184 | 0.9014 | 0.9323 | 3.0171 | |||
| MCF 10A | NM | Basal B | Methylglyoxal | 432 | uM | 13551.184 | 0.6049 | 0.6931 | 3.0171 | |||
| MCF 10A | NM | Basal B | Methylglyoxal | 2160 | uM | 13551.184 | 0.1470 | 0.0593 | 3.0171 | |||
| MCF 10A | NM | Basal B | Methylglyoxal | 10800 | uM | 13551.184 | 0.1670 | 0.1052 | 3.0171 | |||
| MCF 10A | NM | Basal B | Methylglyoxal | 54000 | uM | 13551.184 | 0.0435 | -0.2926 | 3.0171 | |||
| MCF 10F | NM | - | Methylglyoxal | 0.138 | uM | 13672.184 | 0.9601 | 0.9659 | 2.3721 | |||
| MCF 10F | NM | - | Methylglyoxal | 0.691 | uM | 13672.184 | 0.9340 | 0.9433 | 2.3721 | |||
| MCF 10F | NM | - | Methylglyoxal | 3.46 | uM | 13672.184 | 0.9318 | 0.9414 | 2.3721 | |||
| MCF 10F | NM | - | Methylglyoxal | 17.3 | uM | 13672.184 | 0.9228 | 0.9334 | 2.3721 | |||
| MCF 10F | NM | - | Methylglyoxal | 86.4 | uM | 13672.184 | 0.6227 | 0.6379 | 2.3721 | |||
| MCF 10F | NM | - | Methylglyoxal | 432 | uM | 13672.184 | 0.6094 | 0.6231 | 2.3721 | |||
| MCF 10F | NM | - | Methylglyoxal | 2160 | uM | 13672.184 | 0.0972 | -0.2513 | 2.3721 | |||
| MCF 10F | NM | - | Methylglyoxal | 10800 | uM | 13672.184 | 0.0090 | -0.7252 | 2.3721 | |||
| MCF 10F | NM | - | Methylglyoxal | 54000 | uM | 13672.184 | 0.0002 | -0.9500 | 2.3721 | |||
| MCF12A | NM | Basal B | Methylglyoxal | 0.138 | uM | 13508.184 | 1.0223 | 1.0200 | 2.2235 | |||
| MCF12A | NM | Basal B | Methylglyoxal | 0.691 | uM | 13508.184 | 1.0966 | 1.0847 | 2.2235 |