Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Methylglyoxal | 3.46 | uM | 13030.184 | 1.0804 | 1.2892 | 0.5725 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 17.3 | uM | 13030.184 | 0.8346 | 0.4583 | 0.5725 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 86.4 | uM | 13030.184 | 0.8219 | 0.4199 | 0.5725 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 432 | uM | 13030.184 | 0.5769 | -0.2349 | 0.5725 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 2160 | uM | 13030.184 | 0.0275 | -0.9962 | 0.5725 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 10800 | uM | 13030.184 | 0.0405 | -0.9926 | 0.5725 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 54000 | uM | 13030.184 | 0.0005 | -1.0000 | 0.5725 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 0.138 | uM | 13149.184 | 0.9744 | 0.9409 | 0.8650 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 0.691 | uM | 13149.184 | 0.9609 | 0.9099 | 0.8650 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 3.46 | uM | 13149.184 | 0.9922 | 0.9819 | 0.8650 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 17.3 | uM | 13149.184 | 0.8641 | 0.6893 | 0.8650 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 86.4 | uM | 13149.184 | 0.7971 | 0.5387 | 0.8650 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 432 | uM | 13149.184 | 0.6870 | 0.2957 | 0.8650 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 2160 | uM | 13149.184 | 0.0940 | -0.8700 | 0.8650 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 10800 | uM | 13149.184 | 0.1762 | -0.7314 | 0.8650 | |||
| AU565 | HER2amp | Luminal | Methylglyoxal | 54000 | uM | 13149.184 | 0.0011 | -0.9992 | 0.8650 | |||
| BT-20 | TNBC | Basal A | Methylglyoxal | 0.138 | uM | 13599.184 | 0.9542 | 0.8934 | 0.8566 | |||
| BT-20 | TNBC | Basal A | Methylglyoxal | 0.691 | uM | 13599.184 | 0.9608 | 0.9087 | 0.8566 | |||
| BT-20 | TNBC | Basal A | Methylglyoxal | 3.46 | uM | 13599.184 | 0.9330 | 0.8445 | 0.8566 | |||
| BT-20 | TNBC | Basal A | Methylglyoxal | 17.3 | uM | 13599.184 | 0.8629 | 0.6837 | 0.8566 | |||
| BT-20 | TNBC | Basal A | Methylglyoxal | 86.4 | uM | 13599.184 | 0.9201 | 0.8148 | 0.8566 | |||
| BT-20 | TNBC | Basal A | Methylglyoxal | 432 | uM | 13599.184 | 0.8770 | 0.7160 | 0.8566 | |||
| BT-20 | TNBC | Basal A | Methylglyoxal | 2160 | uM | 13599.184 | 0.0887 | -0.8817 | 0.8566 | |||
| BT-20 | TNBC | Basal A | Methylglyoxal | 10800 | uM | 13599.184 | 0.0688 | -0.9120 | 0.8566 | |||
| BT-20 | TNBC | Basal A | Methylglyoxal | 54000 | uM | 13599.184 | 0.6044 | 0.1110 | 0.8566 |