Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Methylglyoxal | 10800 | uM | 13516.184 | 0.2082 | -0.8760 | 0.5643 | |||
| MDA-MB-361 | HER2amp | Luminal | Methylglyoxal | 54000 | uM | 13516.184 | 0.0068 | -0.9997 | 0.5643 | |||
| MDA-MB-453 | TNBC | Luminal | Methylglyoxal | 0.138 | uM | 13647.184 | 1.0212 | 1.0326 | 1.2942 | |||
| MDA-MB-453 | TNBC | Luminal | Methylglyoxal | 0.691 | uM | 13647.184 | 1.0066 | 1.0102 | 1.2942 | |||
| MDA-MB-453 | TNBC | Luminal | Methylglyoxal | 3.46 | uM | 13647.184 | 0.9983 | 0.9973 | 1.2942 | |||
| MDA-MB-453 | TNBC | Luminal | Methylglyoxal | 17.3 | uM | 13647.184 | 0.9244 | 0.8821 | 1.2942 | |||
| MDA-MB-453 | TNBC | Luminal | Methylglyoxal | 86.4 | uM | 13647.184 | 0.9505 | 0.9231 | 1.2942 | |||
| MDA-MB-453 | TNBC | Luminal | Methylglyoxal | 432 | uM | 13647.184 | 0.8618 | 0.7828 | 1.2942 | |||
| MDA-MB-453 | TNBC | Luminal | Methylglyoxal | 2160 | uM | 13647.184 | 0.4918 | 0.1559 | 1.2942 | |||
| MDA-MB-453 | TNBC | Luminal | Methylglyoxal | 10800 | uM | 13647.184 | 0.0277 | -0.8749 | 1.2942 | |||
| MDA-MB-453 | TNBC | Luminal | Methylglyoxal | 54000 | uM | 13647.184 | 1.0411 | 1.0632 | 1.2942 | |||
| MX1 | Unknown | Unknown | Methylglyoxal | 0.138 | uM | 13567.184 | 0.9537 | 0.8676 | 0.6921 | |||
| MX1 | Unknown | Unknown | Methylglyoxal | 0.691 | uM | 13567.184 | 0.9257 | 0.7890 | 0.6921 | |||
| MX1 | Unknown | Unknown | Methylglyoxal | 3.46 | uM | 13567.184 | 0.9748 | 0.9277 | 0.6921 | |||
| MX1 | Unknown | Unknown | Methylglyoxal | 17.3 | uM | 13567.184 | 0.9331 | 0.8097 | 0.6921 | |||
| MX1 | Unknown | Unknown | Methylglyoxal | 86.4 | uM | 13567.184 | 0.9064 | 0.7352 | 0.6921 | |||
| MX1 | Unknown | Unknown | Methylglyoxal | 432 | uM | 13567.184 | 0.8523 | 0.5877 | 0.6921 | |||
| MX1 | Unknown | Unknown | Methylglyoxal | 2160 | uM | 13567.184 | 0.1018 | -0.9263 | 0.6921 | |||
| MX1 | Unknown | Unknown | Methylglyoxal | 10800 | uM | 13567.184 | 0.0188 | -0.9936 | 0.6921 | |||
| MX1 | Unknown | Unknown | Methylglyoxal | 54000 | uM | 13567.184 | 0.0063 | -0.9987 | 0.6921 | |||
| SK-BR-3 | HER2amp | Luminal | Methylglyoxal | 0.138 | uM | 13615.184 | 0.9360 | 0.8918 | 1.1889 | |||
| SK-BR-3 | HER2amp | Luminal | Methylglyoxal | 0.691 | uM | 13615.184 | 0.9511 | 0.9174 | 1.1889 | |||
| SK-BR-3 | HER2amp | Luminal | Methylglyoxal | 3.46 | uM | 13615.184 | 0.9144 | 0.8549 | 1.1889 | |||
| SK-BR-3 | HER2amp | Luminal | Methylglyoxal | 17.3 | uM | 13615.184 | 0.8242 | 0.6998 | 1.1889 | |||
| SK-BR-3 | HER2amp | Luminal | Methylglyoxal | 86.4 | uM | 13615.184 | 0.8012 | 0.6598 | 1.1889 |