Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14227.189 | 0.2703 | -0.2854 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14227.189 | 0.2703 | -0.2854 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14227.189 | 0.4471 | 0.0618 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14227.189 | 0.4471 | 0.0618 | 1.2712 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11660.145 | 1.0000 | 1.0000 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11660.145 | 1.0000 | 1.0000 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11660.145 | 0.9676 | 0.9293 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11660.145 | 0.9676 | 0.9293 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11660.145 | 1.0114 | 1.0248 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11660.145 | 1.0114 | 1.0248 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11660.145 | 0.9920 | 0.9826 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11660.145 | 0.9920 | 0.9826 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11660.145 | 0.9678 | 0.9299 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11660.145 | 0.9678 | 0.9299 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11660.145 | 0.7290 | 0.4168 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11660.145 | 0.7290 | 0.4168 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11660.145 | 0.3825 | -0.2988 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11660.145 | 0.3825 | -0.2988 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11660.145 | 0.1688 | -0.7127 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11660.145 | 0.1688 | -0.7127 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11660.145 | 0.0820 | -0.8693 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11660.145 | 0.0820 | -0.8693 | 0.9169 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12003.145 | 1.0246 | 1.0512 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12003.145 | 1.0246 | 1.0512 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12003.145 | 0.9629 | 0.9228 | 0.9611 |