Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7465.098 | 0.9029 | 0.8392 | 1.2188 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7465.098 | 0.8806 | 0.8018 | 1.2188 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7465.098 | 0.8451 | 0.7421 | 1.2188 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7466.098 | 0.9941 | 0.9857 | 0.8226 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7466.098 | 0.9262 | 0.8220 | 0.8226 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7466.098 | 0.9594 | 0.9017 | 0.8226 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7466.098 | 0.9999 | 0.9997 | 0.8226 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7466.098 | 0.9843 | 0.9618 | 0.8226 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7466.098 | 0.9372 | 0.8483 | 0.8226 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7466.098 | 0.9732 | 0.9350 | 0.8226 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7466.098 | 0.9591 | 0.9011 | 0.8226 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7466.098 | 0.8652 | 0.6772 | 0.8226 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7467.098 | 1.0178 | 1.0250 | 1.4178 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7467.098 | 0.9598 | 0.9430 | 1.4178 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7467.098 | 0.9997 | 0.9995 | 1.4178 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7467.098 | 1.0476 | 1.0667 | 1.4178 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7467.098 | 1.0195 | 1.0274 | 1.4178 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7467.098 | 0.9892 | 0.9847 | 1.4178 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7467.098 | 1.0095 | 1.0134 | 1.4178 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7467.098 | 1.0693 | 1.0968 | 1.4178 | |
| HCC3153 | TNBC | Basal A | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7467.098 | 0.9652 | 0.9507 | 1.4178 | |
| HCC38 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7469.098 | 0.9813 | 0.9814 | 2.0111 | |
| HCC38 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7469.098 | 0.9658 | 0.9656 | 2.0111 | |
| HCC38 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7469.098 | 1.1341 | 1.1292 | 2.0111 | |
| HCC38 | TNBC | Basal B | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7469.098 | 0.9811 | 0.9812 | 2.0111 |