Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7466.095 | 1.0051 | 1.0117 | 0.8699 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7466.095 | 1.0317 | 1.0730 | 0.8699 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7466.095 | 0.7245 | 0.3809 | 0.8699 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7466.095 | 0.2572 | -0.5802 | 0.8699 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7466.095 | 0.2113 | -0.6650 | 0.8699 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7466.095 | 0.2394 | -0.6133 | 0.8699 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7466.095 | 0.3413 | -0.4188 | 0.8699 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7466.095 | 0.0083 | -0.9919 | 0.8699 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7467.095 | 0.9704 | 0.9531 | 1.2671 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7467.095 | 0.9706 | 0.9535 | 1.2671 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7467.095 | 0.8368 | 0.7377 | 1.2671 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7467.095 | 0.3207 | -0.1848 | 1.2671 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7467.095 | 0.2269 | -0.3797 | 1.2671 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7467.095 | 0.2102 | -0.4159 | 1.2671 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7467.095 | 0.2167 | -0.4017 | 1.2671 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7467.095 | 0.2175 | -0.4000 | 1.2671 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7467.095 | 0.0083 | -0.9545 | 1.2671 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7468.095 | 1.0495 | 1.0679 | 1.4474 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7468.095 | 0.9976 | 0.9967 | 1.4474 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7468.095 | 0.7811 | 0.6861 | 1.4474 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7468.095 | 0.2209 | -0.2954 | 1.4474 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7468.095 | 0.1522 | -0.4552 | 1.4474 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7468.095 | 0.1549 | -0.4485 | 1.4474 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7468.095 | 0.1653 | -0.4233 | 1.4474 | |
| HCC38 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7468.095 | 0.0980 | -0.5982 | 1.4474 |