Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0632 | uM | 5911.094 | 0.1840 | -0.6229 | 1.0146 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5911.094 | 0.2304 | -0.5294 | 1.0146 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5911.094 | 0.4649 | -0.0600 | 1.0146 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5911.094 | 0.4227 | -0.1440 | 1.0146 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.5 | uM | 5911.094 | 0.0060 | -0.9872 | 1.0146 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 197 | uM | 5911.094 | 0.5317 | 0.0732 | 1.0146 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5912.095 | 0.9787 | 0.9573 | 0.9981 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5912.095 | 0.8425 | 0.6845 | 0.9981 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5912.095 | 0.2082 | -0.5849 | 0.9981 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5912.095 | 0.1322 | -0.7365 | 0.9981 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5912.095 | 0.1171 | -0.7668 | 0.9981 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5912.095 | 0.0891 | -0.8227 | 0.9981 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5912.095 | 0.1415 | -0.7181 | 0.9981 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5912.095 | 0.2983 | -0.4049 | 0.9981 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5912.095 | 0.0067 | -0.9867 | 0.9981 | |
| HCC1143 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7430.095 | 0.9802 | 0.9795 | 1.9390 | |
| HCC1143 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7430.095 | 0.9561 | 0.9542 | 1.9390 | |
| HCC1143 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7430.095 | 0.8287 | 0.8153 | 1.9390 | |
| HCC1143 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7430.095 | 0.5525 | 0.4729 | 1.9390 | |
| HCC1143 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7430.095 | 0.3474 | 0.1594 | 1.9390 | |
| HCC1143 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7430.095 | 0.2629 | 0.0041 | 1.9390 | |
| HCC1143 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7430.095 | 0.2881 | 0.0527 | 1.9390 | |
| HCC1143 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7430.095 | 0.2857 | 0.0482 | 1.9390 | |
| HCC1143 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7430.095 | 0.0050 | -0.8702 | 1.9390 | |
| HCC1187 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7431.095 | 1.0028 | 1.0043 | 1.2776 |