Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0632 | uM | 7463.094 | 0.8485 | 0.5521 | 0.6482 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7463.094 | 1.0292 | 1.0908 | 0.6482 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7463.094 | 1.3357 | 2.1256 | 0.6482 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7463.094 | 0.1528 | -0.8897 | 0.6482 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 39.5 | uM | 7463.094 | 0.0044 | -0.9995 | 0.6482 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 197 | uM | 7463.094 | 1.1731 | 1.5584 | 0.6482 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7464.095 | 1.0125 | 1.0462 | 0.5464 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7464.095 | 1.0045 | 1.0164 | 0.5464 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7464.095 | 0.9175 | 0.7084 | 0.5464 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7464.095 | 0.6984 | 0.0368 | 0.5464 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7464.095 | 0.5874 | -0.2448 | 0.5464 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7464.095 | 0.6158 | -0.1765 | 0.5464 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7464.095 | 0.8082 | 0.3546 | 0.5464 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7464.095 | 1.2469 | 1.9950 | 0.5464 | |
| HCC2185 | TNBC | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7464.095 | 0.0102 | -0.9996 | 0.5464 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7465.095 | 1.0376 | 1.0587 | 1.2754 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7465.095 | 0.8795 | 0.8084 | 1.2754 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7465.095 | 0.8989 | 0.8396 | 1.2754 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7465.095 | 0.5222 | 0.2017 | 1.2754 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7465.095 | 0.2443 | -0.3377 | 1.2754 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7465.095 | 0.2049 | -0.4228 | 1.2754 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7465.095 | 0.2437 | -0.3389 | 1.2754 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7465.095 | 0.3574 | -0.1073 | 1.2754 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7465.095 | 0.0097 | -0.9474 | 1.2754 | |
| HCC3153 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7466.095 | 1.0325 | 1.0749 | 0.8699 |