Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5908.095 | 0.7515 | 0.1310 | 0.5012 | |
| BT-483 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5908.095 | 0.7785 | 0.2136 | 0.5012 | |
| BT-483 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5908.095 | 0.8235 | 0.3577 | 0.5012 | |
| BT-483 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5908.095 | 0.0106 | -0.9998 | 0.5012 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5909.095 | 1.1012 | 1.0708 | 2.7716 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5909.095 | 1.0971 | 1.0680 | 2.7716 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5909.095 | 0.9235 | 0.9434 | 2.7716 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5909.095 | 0.3906 | 0.4247 | 2.7716 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5909.095 | 0.2215 | 0.1611 | 2.7716 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5909.095 | 0.1124 | -0.0911 | 2.7716 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5909.095 | 0.0900 | -0.1610 | 2.7716 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5909.095 | 0.0067 | -0.6713 | 2.7716 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5909.095 | 0.0004 | -0.8830 | 2.7716 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 5910.095 | 0.9834 | 0.9898 | 3.2727 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5910.095 | 1.0237 | 1.0144 | 3.2727 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 5910.095 | 0.5860 | 0.6986 | 3.2727 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5910.095 | 0.2010 | 0.2250 | 3.2727 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 5910.095 | 0.0930 | -0.0320 | 3.2727 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 5910.095 | 0.0636 | -0.1380 | 3.2727 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 5910.095 | 0.0344 | -0.2856 | 3.2727 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 5910.095 | 0.0331 | -0.2942 | 3.2727 | |
| BT-549 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 5910.095 | 0.0004 | -0.8108 | 3.2727 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 5911.094 | 0.9471 | 0.8956 | 1.0146 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00253 | uM | 5911.094 | 0.4400 | -0.1095 | 1.0146 | |
| CAMA-1 | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 5911.094 | 0.2022 | -0.5863 | 1.0146 |