Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 10580.1 | 0.8997 | 0.7516 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 10580.1 | 0.9025 | 0.7585 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 10580.1 | 0.9321 | 0.8311 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 10580.1 | 0.9782 | 0.9455 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 10580.1 | 0.9363 | 0.8413 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 10580.1 | 1.0041 | 1.0103 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 10580.1 | 0.0280 | -0.9775 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 10580.1 | 0.0129 | -0.9915 | 0.7968 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 7553.093 | 0.9699 | 0.9472 | 1.1429 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 7553.093 | 0.9521 | 0.9159 | 1.1429 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 7553.093 | 0.9739 | 0.9542 | 1.1429 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 7553.093 | 0.9930 | 0.9877 | 1.1429 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 7553.093 | 0.9560 | 0.9228 | 1.1429 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 7553.093 | 0.9299 | 0.8767 | 1.1429 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 7553.093 | 0.9138 | 0.8483 | 1.1429 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 7553.093 | 0.0585 | -0.8332 | 1.1429 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 7553.093 | 0.0118 | -0.9589 | 1.1429 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 10444.093 | 0.9719 | 0.9484 | 1.0902 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 10444.093 | 0.9138 | 0.8413 | 1.0902 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 10444.093 | 0.9399 | 0.8894 | 1.0902 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 10444.093 | 0.9846 | 0.9717 | 1.0902 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 10444.093 | 0.9604 | 0.9272 | 1.0902 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 10444.093 | 0.9147 | 0.8429 | 1.0902 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 10444.093 | 0.9162 | 0.8457 | 1.0902 | |
| ZR-75-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 10444.093 | 0.0371 | -0.9027 | 1.0902 |