Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.0213 | uM | 7545.1 | 0.9470 | 0.9067 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.107 | uM | 7545.1 | 1.0002 | 1.0004 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.533 | uM | 7545.1 | 0.9743 | 0.9549 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 2.67 | uM | 7545.1 | 0.8461 | 0.7272 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 13.3 | uM | 7545.1 | 0.0112 | -0.9613 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 66.7 | uM | 7545.1 | 0.0093 | -0.9669 | 1.1396 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 7547.093 | 0.9473 | 0.9046 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 7547.093 | 0.7534 | 0.5492 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 7547.093 | 0.9198 | 0.8547 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 7547.093 | 0.8958 | 0.8111 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 7547.093 | 0.9809 | 0.9656 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 7547.093 | 0.8626 | 0.7503 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 7547.093 | 0.9167 | 0.8490 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 7547.093 | 0.0206 | -0.9398 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 7547.093 | 0.0134 | -0.9590 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 10420.093 | 0.8508 | 0.5010 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 10420.093 | 0.9640 | 0.8739 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 10420.093 | 0.9115 | 0.6964 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 10420.093 | 0.9855 | 0.9487 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 10420.093 | 1.0049 | 1.0173 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 10420.093 | 0.9554 | 0.8444 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 10420.093 | 0.9814 | 0.9345 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 10420.093 | 0.0312 | -0.9958 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 10420.093 | 0.0105 | -0.9994 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 10580.1 | 0.9794 | 0.9485 | 0.7968 |