Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7504.095 | 0.0003 | -0.9613 | 2.0796 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7506.095 | 1.0239 | 1.0389 | 1.2246 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7506.095 | 0.9854 | 0.9761 | 1.2246 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7506.095 | 0.9631 | 0.9395 | 1.2246 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7506.095 | 0.7580 | 0.5950 | 1.2246 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7506.095 | 0.4951 | 0.1265 | 1.2246 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7506.095 | 0.4135 | -0.0275 | 1.2246 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7506.095 | 0.4095 | -0.0354 | 1.2246 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7506.095 | 0.6102 | 0.3361 | 1.2246 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7506.095 | 0.0226 | -0.9094 | 1.2246 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7507.094 | 1.0019 | 1.0037 | 1.0418 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00253 | uM | 7507.094 | 0.5952 | 0.2155 | 1.0418 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7507.094 | 0.4261 | -0.1181 | 1.0418 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0632 | uM | 7507.094 | 0.3765 | -0.2169 | 1.0418 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7507.094 | 0.3644 | -0.2411 | 1.0418 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7507.094 | 0.5796 | 0.1848 | 1.0418 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7507.094 | 0.5343 | 0.0958 | 1.0418 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 39.5 | uM | 7507.094 | 0.0072 | -0.9825 | 1.0418 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 197 | uM | 7507.094 | 0.5109 | 0.0497 | 1.0418 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7508.095 | 0.9985 | 0.9960 | 0.7473 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7508.095 | 0.9225 | 0.7954 | 0.7473 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7508.095 | 0.4679 | -0.2762 | 0.7473 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7508.095 | 0.3756 | -0.4606 | 0.7473 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7508.095 | 0.3126 | -0.5781 | 0.7473 | |
| MDA-MB-361 | HER2amp | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7508.095 | 0.2723 | -0.6492 | 0.7473 |