Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 7470.093 | 1.0119 | 1.0221 | 1.0798 | |
| HCC70 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 7470.093 | 1.0352 | 1.0652 | 1.0798 | |
| HCC70 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 7470.093 | 0.9162 | 0.8443 | 1.0798 | |
| HCC70 | TNBC | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 7470.093 | 0.7731 | 0.5758 | 1.0798 | |
| HCC70 | TNBC | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 7470.093 | 0.0106 | -0.9704 | 1.0798 | |
| HCC70 | TNBC | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 7470.093 | 0.0110 | -0.9694 | 1.0798 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 7472.1 | 1.5149 | 1.9057 | 1.1120 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 7472.1 | 1.4635 | 1.8168 | 1.1120 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 7472.1 | 1.0189 | 1.0340 | 1.1120 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 7472.1 | 1.5356 | 1.9414 | 1.1120 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 7472.1 | 1.2725 | 1.4840 | 1.1120 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 7472.1 | 1.2222 | 1.3955 | 1.1120 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 7472.1 | 2.0813 | 2.8664 | 1.1120 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 7472.1 | 0.0011 | -0.9955 | 1.1120 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 7472.1 | 0.0007 | -0.9972 | 1.1120 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 10379.093 | 1.0478 | 1.0415 | 2.2706 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 10379.093 | 0.9984 | 0.9986 | 2.2706 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 10379.093 | 1.0043 | 1.0038 | 2.2706 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 10379.093 | 1.0454 | 1.0395 | 2.2706 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 10379.093 | 1.0450 | 1.0392 | 2.2706 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 10379.093 | 1.0148 | 1.0129 | 2.2706 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 10379.093 | 0.6843 | 0.6923 | 2.2706 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 10379.093 | 0.0102 | -0.7349 | 2.2706 | |
| Hs 578T | TNBC | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 10379.093 | 0.0102 | -0.7349 | 2.2706 | |
| LY2 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 10380.093 | 1.0452 | 1.0604 | 1.4880 |