Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 10380.093 | 1.0642 | 1.0854 | 1.4880 | |
| LY2 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 10380.093 | 1.0754 | 1.1001 | 1.4880 | |
| LY2 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 10380.093 | 1.0723 | 1.0961 | 1.4880 | |
| LY2 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 10380.093 | 1.0122 | 1.0163 | 1.4880 | |
| LY2 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 10380.093 | 1.0369 | 1.0493 | 1.4880 | |
| LY2 | HR+ | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 10380.093 | 0.9871 | 0.9826 | 1.4880 | |
| LY2 | HR+ | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 10380.093 | 0.0132 | -0.8911 | 1.4880 | |
| LY2 | HR+ | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 10380.093 | 0.0097 | -0.9112 | 1.4880 | |
| MCF 10A | NM | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 7485.093 | 0.9646 | 0.9799 | 3.5766 | |
| MCF 10A | NM | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 7485.093 | 1.0431 | 1.0237 | 3.5766 | |
| MCF 10A | NM | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 7485.093 | 0.9169 | 0.9521 | 3.5766 | |
| MCF 10A | NM | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 7485.093 | 0.9550 | 0.9744 | 3.5766 | |
| MCF 10A | NM | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 7485.093 | 0.9397 | 0.9655 | 3.5766 | |
| MCF 10A | NM | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 7485.093 | 0.9225 | 0.9554 | 3.5766 | |
| MCF 10A | NM | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 7485.093 | 0.5560 | 0.6973 | 3.5766 | |
| MCF 10A | NM | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 7485.093 | 0.0099 | -0.4491 | 3.5766 | |
| MCF 10A | NM | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 7485.093 | 0.0083 | -0.4760 | 3.5766 | |
| MCF 10F | NM | - | IKK16 | IKK | NFKB | 0.000171 | uM | 7486.1 | 1.1238 | 1.2405 | 1.0281 | |
| MCF 10F | NM | - | IKK16 | IKK | NFKB | 0.000853 | uM | 7486.1 | 1.0500 | 1.0971 | 1.0281 | |
| MCF 10F | NM | - | IKK16 | IKK | NFKB | 0.00427 | uM | 7486.1 | 0.9683 | 0.9384 | 1.0281 | |
| MCF 10F | NM | - | IKK16 | IKK | NFKB | 0.0213 | uM | 7486.1 | 1.1152 | 1.2237 | 1.0281 | |
| MCF 10F | NM | - | IKK16 | IKK | NFKB | 0.107 | uM | 7486.1 | 1.0926 | 1.1800 | 1.0281 | |
| MCF 10F | NM | - | IKK16 | IKK | NFKB | 0.533 | uM | 7486.1 | 0.9892 | 0.9789 | 1.0281 | |
| MCF 10F | NM | - | IKK16 | IKK | NFKB | 2.67 | uM | 7486.1 | 0.9273 | 0.8585 | 1.0281 | |
| MCF 10F | NM | - | IKK16 | IKK | NFKB | 13.3 | uM | 7486.1 | 0.0166 | -0.9629 | 1.0281 |