Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 5904.1 | 0.9085 | 0.8615 | 1.3369 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 5904.1 | 0.9976 | 0.9964 | 1.3369 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 5904.1 | 0.9636 | 0.9453 | 1.3369 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 5904.1 | 0.7913 | 0.6787 | 1.3369 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 5904.1 | 0.0363 | -0.8326 | 1.3369 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 5904.1 | 0.0099 | -0.9364 | 1.3369 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 10385.093 | 1.0583 | 1.1953 | 0.6082 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 10385.093 | 1.0020 | 1.0066 | 0.6082 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 10385.093 | 1.0050 | 1.0165 | 0.6082 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 10385.093 | 1.0908 | 1.3072 | 0.6082 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 10385.093 | 1.0588 | 1.1970 | 0.6082 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 10385.093 | 0.9825 | 0.9428 | 0.6082 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 10385.093 | 0.9538 | 0.8504 | 0.6082 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 10385.093 | 0.0266 | -0.9949 | 0.6082 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 10385.093 | 0.0102 | -0.9989 | 0.6082 | |
| BT-474 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 5905.093 | 1.0301 | 1.0662 | 0.9101 | |
| BT-474 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 5905.093 | 1.0755 | 1.1666 | 0.9101 | |
| BT-474 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 5905.093 | 1.0053 | 1.0116 | 0.9101 | |
| BT-474 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 5905.093 | 1.1029 | 1.2272 | 0.9101 | |
| BT-474 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 5905.093 | 1.0499 | 1.1100 | 0.9101 | |
| BT-474 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 5905.093 | 1.0198 | 1.0436 | 0.9101 | |
| BT-474 | HER2amp | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 5905.093 | 1.0002 | 1.0004 | 0.9101 | |
| BT-474 | HER2amp | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 5905.093 | 0.0270 | -0.9622 | 0.9101 | |
| BT-474 | HER2amp | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 5905.093 | 0.0115 | -0.9852 | 0.9101 | |
| BT-549 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 5909.093 | 1.0555 | 1.0378 | 2.8805 |