Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 5909.093 | 1.0674 | 1.0458 | 2.8805 | |
| BT-549 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 5909.093 | 1.0575 | 1.0392 | 2.8805 | |
| BT-549 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 5909.093 | 1.0800 | 1.0541 | 2.8805 | |
| BT-549 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 5909.093 | 0.9874 | 0.9912 | 2.8805 | |
| BT-549 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.533 | uM | 5909.093 | 0.9692 | 0.9784 | 2.8805 | |
| BT-549 | TNBC | Basal B | IKK16 | IKK | NFKB | 2.67 | uM | 5909.093 | 0.7592 | 0.8176 | 2.8805 | |
| BT-549 | TNBC | Basal B | IKK16 | IKK | NFKB | 13.3 | uM | 5909.093 | 0.0064 | -0.6538 | 2.8805 | |
| BT-549 | TNBC | Basal B | IKK16 | IKK | NFKB | 66.7 | uM | 5909.093 | 0.0028 | -0.7387 | 2.8805 | |
| CAMA-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 10473.1 | 0.9400 | 0.9114 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 10473.1 | 0.9141 | 0.8726 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 10473.1 | 0.9225 | 0.8853 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 10473.1 | 1.0440 | 1.0641 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 10473.1 | 0.9789 | 0.9689 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 10473.1 | 0.9288 | 0.8947 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 10473.1 | 0.7025 | 0.5442 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 10473.1 | 0.0137 | -0.9135 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 10473.1 | 0.0069 | -0.9480 | 1.3652 | |
| HCC1143 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 7430.093 | 0.9988 | 0.9988 | 1.9432 | |
| HCC1143 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 7430.093 | 1.0335 | 1.0342 | 1.9432 | |
| HCC1143 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 7430.093 | 0.9721 | 0.9711 | 1.9432 | |
| HCC1143 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 7430.093 | 1.0514 | 1.0523 | 1.9432 | |
| HCC1143 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 7430.093 | 1.0071 | 1.0073 | 1.9432 | |
| HCC1143 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 7430.093 | 0.9831 | 0.9825 | 1.9432 | |
| HCC1143 | TNBC | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 7430.093 | 0.9153 | 0.9110 | 1.9432 | |
| HCC1143 | TNBC | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 7430.093 | 0.0071 | -0.8428 | 1.9432 |