Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | IKK16 | IKK | NFKB | 0.533 | uM | 5897.093 | 0.9293 | 0.8818 | 1.2047 | |
| 184B5 | NM | Basal | IKK16 | IKK | NFKB | 2.67 | uM | 5897.093 | 0.4960 | 0.1176 | 1.2047 | |
| 184B5 | NM | Basal | IKK16 | IKK | NFKB | 13.3 | uM | 5897.093 | 0.0130 | -0.9457 | 1.2047 | |
| 184B5 | NM | Basal | IKK16 | IKK | NFKB | 66.7 | uM | 5897.093 | 0.0121 | -0.9487 | 1.2047 | |
| 600MPE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 5898.093 | 0.9713 | 0.9181 | 0.6963 | |
| 600MPE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 5898.093 | 0.9058 | 0.7350 | 0.6963 | |
| 600MPE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 5898.093 | 0.9770 | 0.9341 | 0.6963 | |
| 600MPE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 5898.093 | 0.9111 | 0.7496 | 0.6963 | |
| 600MPE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 5898.093 | 0.9678 | 0.9082 | 0.6963 | |
| 600MPE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 5898.093 | 0.9943 | 0.9837 | 0.6963 | |
| 600MPE | HR+ | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 5898.093 | 0.9778 | 0.9365 | 0.6963 | |
| 600MPE | HR+ | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 5898.093 | 0.0142 | -0.9956 | 0.6963 | |
| 600MPE | HR+ | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 5898.093 | 0.0087 | -0.9978 | 0.6963 | |
| AU565 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 5900.093 | 1.0737 | 1.0625 | 2.3084 | |
| AU565 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 5900.093 | 1.0125 | 1.0108 | 2.3084 | |
| AU565 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 5900.093 | 1.0197 | 1.0170 | 2.3084 | |
| AU565 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 5900.093 | 1.0103 | 1.0089 | 2.3084 | |
| AU565 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 5900.093 | 0.9688 | 0.9727 | 2.3084 | |
| AU565 | HER2amp | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 5900.093 | 0.9038 | 0.9142 | 2.3084 | |
| AU565 | HER2amp | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 5900.093 | 0.6098 | 0.6143 | 2.3084 | |
| AU565 | HER2amp | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 5900.093 | 0.0244 | -0.5995 | 2.3084 | |
| AU565 | HER2amp | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 5900.093 | 0.0063 | -0.7771 | 2.3084 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 5904.1 | 1.0097 | 1.0145 | 1.3369 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 5904.1 | 0.9060 | 0.8576 | 1.3369 | |
| BT-20 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 5904.1 | 1.0364 | 1.0543 | 1.3369 |