Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7793.001 | 1.0421 | 1.0729 | 1.1508 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7793.001 | 1.1006 | 1.1738 | 1.1508 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7793.001 | 1.0147 | 1.0255 | 1.1508 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7793.001 | 0.8348 | 0.7096 | 1.1508 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7793.001 | 0.0604 | -0.8254 | 1.1508 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 7793.001 | 0.0789 | -0.7798 | 1.1508 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 7793.001 | 0.1834 | -0.5418 | 1.1508 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 7793.001 | 0.4273 | -0.0447 | 1.1508 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 7793.001 | 0.0280 | -0.9105 | 1.1508 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9035.001 | 1.0022 | 1.0018 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9035.001 | 0.9423 | 0.9517 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9035.001 | 0.0777 | -0.3013 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9035.001 | 0.0531 | -0.4029 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9035.001 | 0.0391 | -0.4736 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 9035.001 | 0.0616 | -0.3649 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 9035.001 | 0.1170 | -0.1732 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 9035.001 | 0.3311 | 0.2689 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 9035.001 | 0.2982 | 0.2153 | 2.4291 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9146.001 | 1.0332 | 1.0514 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9146.001 | 0.9469 | 0.9171 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9146.001 | 0.9030 | 0.8477 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9146.001 | 0.7330 | 0.5713 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9146.001 | 0.0990 | -0.6680 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 9146.001 | 0.1426 | -0.5592 | 1.2878 | |
| AU565 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 9146.001 | 0.2712 | -0.2741 | 1.2878 |