Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 5912.071 | 0.9543 | 0.9245 | 1.2176 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 5912.071 | 0.9638 | 0.9404 | 1.2176 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 5912.071 | 0.9306 | 0.8853 | 1.2176 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.192 | uM | 5912.071 | 0.9332 | 0.8896 | 1.2176 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.96 | uM | 5912.071 | 0.9953 | 0.9923 | 1.2176 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 4.8 | uM | 5912.071 | 0.7931 | 0.6533 | 1.2176 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 24 | uM | 5912.071 | 0.0336 | -0.8766 | 1.2176 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 120 | uM | 5912.071 | 0.0281 | -0.8936 | 1.2176 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5912.091 | 1.0225 | 1.0411 | 1.0917 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5912.091 | 1.0232 | 1.0424 | 1.0917 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5912.091 | 1.0380 | 1.0695 | 1.0917 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5912.091 | 1.0635 | 1.1161 | 1.0917 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5912.091 | 1.0302 | 1.0553 | 1.0917 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5912.091 | 1.0023 | 1.0043 | 1.0917 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5912.091 | 1.0218 | 1.0399 | 1.0917 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5912.091 | 1.0729 | 1.1332 | 1.0917 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 5912.091 | 0.0538 | -0.8625 | 1.0917 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5912.098 | 0.9849 | 0.9714 | 1.0559 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5912.098 | 0.9682 | 0.9397 | 1.0559 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5912.098 | 0.9818 | 0.9655 | 1.0559 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5912.098 | 0.9851 | 0.9717 | 1.0559 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5912.098 | 0.9752 | 0.9530 | 1.0559 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5912.098 | 1.0472 | 1.0893 | 1.0559 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5912.098 | 0.9666 | 0.9366 | 1.0559 | |
CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5912.098 | 1.0448 | 1.0848 | 1.0559 |