Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5902.091 | 0.9926 | 0.9873 | 1.1648 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5902.091 | 0.0600 | -0.8214 | 1.1648 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 5902.091 | 0.4060 | -0.0775 | 1.1648 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5902.098 | 1.0080 | 1.0143 | 1.1137 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5902.098 | 1.0540 | 1.0968 | 1.1137 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5902.098 | 0.9572 | 0.9229 | 1.1137 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5902.098 | 0.9989 | 0.9980 | 1.1137 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5902.098 | 1.0089 | 1.0160 | 1.1137 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5902.098 | 1.0065 | 1.0116 | 1.1137 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5902.098 | 1.0799 | 1.1429 | 1.1137 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5902.098 | 0.9951 | 0.9912 | 1.1137 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5902.098 | 0.6760 | 0.4071 | 1.1137 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5903.09 | 0.9904 | 0.9794 | 0.9291 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5903.09 | 0.9542 | 0.9016 | 0.9291 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5903.09 | 0.9393 | 0.8697 | 0.9291 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5903.09 | 0.9944 | 0.9880 | 0.9291 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5903.09 | 0.9634 | 0.9214 | 0.9291 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5903.09 | 0.9050 | 0.7963 | 0.9291 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5903.09 | 0.7630 | 0.4949 | 0.9291 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5903.09 | 0.6357 | 0.2281 | 0.9291 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 5903.09 | 0.4109 | -0.2321 | 0.9291 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5904.092 | 1.0700 | 1.1574 | 0.8933 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5904.092 | 0.9024 | 0.7829 | 0.8933 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5904.092 | 0.9499 | 0.8881 | 0.8933 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5904.092 | 0.9994 | 0.9985 | 0.8933 |