Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 9913.001 | 0.7967 | -0.0515 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 10150.001 | 1.0107 | 1.0665 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 10150.001 | 0.9919 | 0.9509 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 10150.001 | 1.0840 | 1.5625 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 10150.001 | 0.9168 | 0.5318 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 10150.001 | 1.0360 | 1.2293 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 10150.001 | 0.9681 | 0.8102 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 10150.001 | 0.9319 | 0.6105 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 10150.001 | 0.9114 | 0.5041 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 10150.001 | 0.6362 | -0.5015 | 0.3255 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 10151.001 | 1.0790 | 1.3956 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 10151.001 | 0.9937 | 0.9700 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 10151.001 | 1.0915 | 1.4621 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 10151.001 | 0.9813 | 0.9122 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 10151.001 | 0.9873 | 0.9403 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 10151.001 | 0.9824 | 0.9174 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 10151.001 | 1.0367 | 1.1788 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 10151.001 | 0.9349 | 0.7047 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 10151.001 | 0.6136 | -0.3729 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 10267.001 | 1.2255 | 2.3439 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 10267.001 | 1.0354 | 1.1837 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 10267.001 | 1.2208 | 2.3117 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 10267.001 | 0.9472 | 0.7437 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 10267.001 | 1.1045 | 1.5713 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 10267.001 | 1.0998 | 1.5439 | 0.3957 |