Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MB 157 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9039.016 | 0.9251 | 0.7344 | 0.5468 | |
MB 157 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9039.016 | 1.0237 | 1.0874 | 0.5468 | |
MB 157 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9039.016 | 0.9528 | 0.8306 | 0.5468 | |
MB 157 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 0.267 | uM | 9039.016 | 0.9230 | 0.7275 | 0.5468 | |
MB 157 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 1.33 | uM | 9039.016 | 0.9313 | 0.7558 | 0.5468 | |
MB 157 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 6.67 | uM | 9039.016 | 0.8016 | 0.3345 | 0.5468 | |
MB 157 | Unknown | Unknown | Gefitinib | EGFR | ErbB | 33.3 | uM | 9039.016 | 0.4227 | -0.5859 | 0.5468 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7867.016 | 1.0189 | 1.0166 | 2.2657 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7867.016 | 1.0916 | 1.0789 | 2.2657 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7867.016 | 0.9634 | 0.9674 | 2.2657 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7867.016 | 1.0492 | 1.0428 | 2.2657 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7867.016 | 0.9859 | 0.9875 | 2.2657 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7867.016 | 0.9290 | 0.9360 | 2.2657 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7867.016 | 0.2040 | -0.0083 | 2.2657 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7867.016 | 0.1433 | -0.1516 | 2.2657 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7867.016 | 0.0451 | -0.4905 | 2.2657 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7868.016 | 1.0493 | 1.0464 | 2.0998 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7868.016 | 0.9702 | 0.9714 | 2.0998 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7868.016 | 0.9310 | 0.9330 | 2.0998 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7868.016 | 1.0175 | 1.0165 | 2.0998 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7868.016 | 1.0793 | 1.0740 | 2.0998 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7868.016 | 1.0336 | 1.0317 | 2.0998 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7868.016 | 0.2530 | 0.0395 | 2.0998 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7868.016 | 0.1404 | -0.2149 | 2.0998 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7868.016 | 0.0059 | -0.8265 | 2.0998 |