Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7870.016 | 1.0055 | 1.0052 | 2.1045 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7870.016 | 0.9718 | 0.9730 | 2.1045 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7870.016 | 1.0061 | 1.0058 | 2.1045 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7870.016 | 1.0480 | 1.0451 | 2.1045 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7870.016 | 1.0516 | 1.0484 | 2.1045 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7870.016 | 0.8186 | 0.8185 | 2.1045 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7870.016 | 0.1757 | -0.1247 | 2.1045 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7870.016 | 0.1652 | -0.1500 | 2.1045 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7870.016 | 0.0438 | -0.5476 | 2.1045 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9551.132 | 0.9952 | 0.9966 | 2.8612 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9551.132 | 1.0815 | 1.0555 | 2.8612 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9551.132 | 0.9206 | 0.9430 | 2.8612 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9551.132 | 1.0923 | 1.0627 | 2.8612 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9551.132 | 0.9692 | 0.9783 | 2.8612 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 9551.132 | 1.0454 | 1.0313 | 2.8612 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 9551.132 | 0.7367 | 0.7975 | 2.8612 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 9551.132 | 1.1019 | 1.0690 | 2.8612 | |
MCF 10A | NM | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 9551.132 | 0.6830 | 0.7505 | 2.8612 | |
MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7488.016 | 1.0058 | 1.0095 | 1.2238 | |
MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7488.016 | 0.9862 | 0.9774 | 1.2238 | |
MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7488.016 | 0.9844 | 0.9745 | 1.2238 | |
MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7488.016 | 0.9740 | 0.9574 | 1.2238 | |
MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7488.016 | 0.9653 | 0.9431 | 1.2238 | |
MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.267 | uM | 7488.016 | 0.7083 | 0.5089 | 1.2238 | |
MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 1.33 | uM | 7488.016 | 0.2948 | -0.2628 | 1.2238 |