Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.0000853
uM
7870.016
1.0055 1.0052 2.1045
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.000427
uM
7870.016
0.9718 0.9730 2.1045
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.00213
uM
7870.016
1.0061 1.0058 2.1045
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.0107
uM
7870.016
1.0480 1.0451 2.1045
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.0533
uM
7870.016
1.0516 1.0484 2.1045
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.267
uM
7870.016
0.8186 0.8185 2.1045
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
1.33
uM
7870.016
0.1757 -0.1247 2.1045
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
6.67
uM
7870.016
0.1652 -0.1500 2.1045
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
33.3
uM
7870.016
0.0438 -0.5476 2.1045
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.0000853
uM
9551.132
0.9952 0.9966 2.8612
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.000427
uM
9551.132
1.0815 1.0555 2.8612
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.00213
uM
9551.132
0.9206 0.9430 2.8612
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.0107
uM
9551.132
1.0923 1.0627 2.8612
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.0533
uM
9551.132
0.9692 0.9783 2.8612
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
0.267
uM
9551.132
1.0454 1.0313 2.8612
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
1.33
uM
9551.132
0.7367 0.7975 2.8612
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
6.67
uM
9551.132
1.1019 1.0690 2.8612
MCF 10A
NM
Basal B
Gefitinib
EGFR
ErbB
33.3
uM
9551.132
0.6830 0.7505 2.8612
MCF 10F
NM
-
Gefitinib
EGFR
ErbB
0.0000853
uM
7488.016
1.0058 1.0095 1.2238
MCF 10F
NM
-
Gefitinib
EGFR
ErbB
0.000427
uM
7488.016
0.9862 0.9774 1.2238
MCF 10F
NM
-
Gefitinib
EGFR
ErbB
0.00213
uM
7488.016
0.9844 0.9745 1.2238
MCF 10F
NM
-
Gefitinib
EGFR
ErbB
0.0107
uM
7488.016
0.9740 0.9574 1.2238
MCF 10F
NM
-
Gefitinib
EGFR
ErbB
0.0533
uM
7488.016
0.9653 0.9431 1.2238
MCF 10F
NM
-
Gefitinib
EGFR
ErbB
0.267
uM
7488.016
0.7083 0.5089 1.2238
MCF 10F
NM
-
Gefitinib
EGFR
ErbB
1.33
uM
7488.016
0.2948 -0.2628 1.2238