Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	10754.154	0.9368	0.9084	1.3934
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	10754.154	1.0161	1.0231	1.3934
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	10754.154	0.8140	0.7254	1.3934
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	11938.154	0.9090	0.7219	0.6375
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	11938.154	0.8474	0.5426	0.6375
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	11938.154	0.9764	0.9263	0.6375
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	11938.154	0.9690	0.9036	0.6375
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	11938.154	0.9401	0.8154	0.6375
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.267	uM	11938.154	0.9148	0.7391	0.6375
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	11938.154	0.9605	0.8774	0.6375
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	11938.154	0.9314	0.7891	0.6375
UACC-812	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	11938.154	0.8944	0.6788	0.6375
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	11660.154	0.9418	0.8763	0.9388
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	11660.154	0.8921	0.7710	0.9388
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	11660.154	0.9776	0.9523	0.9388
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	11660.154	0.9563	0.9070	0.9388
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	11660.154	0.9298	0.8508	0.9388
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.267	uM	11660.154	0.9678	0.9314	0.9388
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	11660.154	0.9518	0.8974	0.9388
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	11660.154	0.9379	0.8681	0.9388
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	11660.154	0.9291	0.8493	0.9388
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000171	uM	12003.167	0.8394	0.7095	1.1158
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000853	uM	12003.167	0.8720	0.7689	1.1158
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00427	uM	12003.167	0.9586	0.9256	1.1158
ZR-75-1	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0213	uM	12003.167	0.8471	0.7236	1.1158

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)