Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10939.154 | 0.9628 | 0.9556 | 1.6876 | |
| T47DKBLUC | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.000171 | uM | 12608.167 | 0.9934 | 0.9896 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.000853 | uM | 12608.167 | 0.9919 | 0.9873 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.00427 | uM | 12608.167 | 0.9995 | 0.9992 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.0213 | uM | 12608.167 | 1.0080 | 1.0127 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.107 | uM | 12608.167 | 0.9967 | 0.9949 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 0.533 | uM | 12608.167 | 1.0143 | 1.0225 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 2.67 | uM | 12608.167 | 1.0236 | 1.0371 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 13.3 | uM | 12608.167 | 0.9906 | 0.9851 | 1.2681 | |
| T47DKBLUC | Unknown | Unknown | FTase Inhibitor I | Ftase | MAPK | 66.7 | uM | 12608.167 | 0.9885 | 0.9819 | 1.2681 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10580.142 | 1.0091 | 1.0227 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10580.142 | 0.9624 | 0.9069 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10580.142 | 0.9978 | 0.9945 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10580.142 | 1.0266 | 1.0663 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10580.142 | 1.0086 | 1.0215 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10580.142 | 0.9385 | 0.8480 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10580.142 | 0.9784 | 0.9463 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10580.142 | 1.0120 | 1.0298 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10580.142 | 0.8960 | 0.7446 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10754.154 | 1.0136 | 1.0195 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10754.154 | 0.9475 | 0.9241 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10754.154 | 0.9992 | 0.9988 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10754.154 | 0.9814 | 0.9732 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10754.154 | 0.9678 | 0.9535 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10754.154 | 0.9558 | 0.9361 | 1.3934 |