Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9210.011 | 0.6973 | 0.3651 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9210.011 | 0.6303 | 0.2266 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9210.011 | 0.6668 | 0.3020 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0185 | uM | 9210.131 | 0.8844 | 0.7450 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0924 | uM | 9210.131 | 0.7369 | 0.4250 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.462 | uM | 9210.131 | 0.7736 | 0.5039 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 2.31 | uM | 9210.131 | 0.8630 | 0.6981 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 11.6 | uM | 9210.131 | 0.6850 | 0.3139 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 57.8 | uM | 9210.131 | 0.7836 | 0.5255 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 289 | uM | 9210.131 | 0.6711 | 0.2843 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 1440 | uM | 9210.131 | 0.6444 | 0.2276 | 0.9004 | |
| CAMA-1 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 7220 | uM | 9210.131 | 0.6846 | 0.3129 | 0.9004 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7807.011 | 1.0306 | 1.0281 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7807.011 | 1.0155 | 1.0142 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7807.011 | 0.9665 | 0.9688 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7807.011 | 0.2515 | 0.0563 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7807.011 | 0.0729 | -0.4042 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7807.011 | 0.0636 | -0.4409 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7807.011 | 0.0732 | -0.4034 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7807.011 | 0.0595 | -0.4577 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7807.011 | 0.0716 | -0.4094 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7808.011 | 1.1662 | 1.1306 | 2.4301 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7808.011 | 0.8707 | 0.8893 | 2.4301 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7808.011 | 0.8363 | 0.8581 | 2.4301 | |
| HBL-100 | Unknown | Unknown | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7808.011 | 0.2509 | 0.1322 | 2.4301 |