Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-157	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	66.7	uM	12594.167	1.0056	1.0079	1.4099
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	10642.142	0.9840	0.9366	0.5006
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	10642.142	0.9929	0.9716	0.5006
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	10642.142	0.9758	0.9046	0.5006
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	10642.142	1.0012	1.0046	0.5006
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	10642.142	0.9895	0.9584	0.5006
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.267	uM	10642.142	0.9953	0.9814	0.5006
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	10642.142	0.9923	0.9693	0.5006
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	10642.142	1.0284	1.1152	0.5006
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	10642.142	1.0194	1.0785	0.5006
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	10818.154	0.9649	0.8637	0.5056
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	10818.154	0.9620	0.8524	0.5056
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	10818.154	0.9933	0.9734	0.5056
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	10818.154	1.0102	1.0407	0.5056
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	10818.154	1.0128	1.0508	0.5056
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.267	uM	10818.154	0.9506	0.8092	0.5056
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	10818.154	1.0057	1.0228	0.5056
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	10818.154	0.9718	0.8900	0.5056
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	10818.154	0.9861	0.9452	0.5056
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	12126.154	0.9397	0.8034	0.6012
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	12126.154	0.8597	0.5554	0.6012
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	12126.154	0.9292	0.7699	0.6012
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	12126.154	0.8952	0.6635	0.6012
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	12126.154	0.9051	0.6945	0.6012
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	0.267	uM	12126.154	0.9125	0.7174	0.6012

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)