Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7483.084 | 0.9752 | 0.9847 | 3.2830 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7483.084 | 1.0115 | 1.0070 | 3.2830 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7483.084 | 0.9495 | 0.9687 | 3.2830 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7483.084 | 0.8277 | 0.8880 | 3.2830 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7483.084 | 0.0363 | -0.2715 | 3.2830 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7483.084 | 0.0131 | -0.4665 | 3.2830 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7483.084 | 0.0140 | -0.4549 | 3.2830 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7484.084 | 1.1303 | 1.0956 | 2.6217 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7484.084 | 1.0592 | 1.0444 | 2.6217 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7484.084 | 0.9568 | 0.9666 | 2.6217 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7484.084 | 1.0309 | 1.0234 | 2.6217 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7484.084 | 0.9124 | 0.9313 | 2.6217 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7484.084 | 0.7392 | 0.7822 | 2.6217 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7484.084 | 0.0142 | -0.6056 | 2.6217 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7484.084 | 0.0076 | -0.6886 | 2.6217 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7484.084 | 0.0088 | -0.6714 | 2.6217 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7485.085 | 1.0681 | 1.0366 | 3.6369 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7485.085 | 1.0021 | 1.0012 | 3.6369 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7485.085 | 0.9052 | 0.9460 | 3.6369 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7485.085 | 0.9796 | 0.9887 | 3.6369 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7485.085 | 0.9561 | 0.9755 | 3.6369 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7485.085 | 0.5977 | 0.7361 | 3.6369 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7485.085 | 0.0136 | -0.3861 | 3.6369 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7485.085 | 0.0074 | -0.4817 | 3.6369 | |
| MCF 10A | NM | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7485.085 | 0.0036 | -0.5759 | 3.6369 |