Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7437.084 | 0.9556 | 0.8014 | 0.4343 | |
| HCC1419 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7437.084 | 0.8757 | 0.4733 | 0.4343 | |
| HCC1419 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7437.084 | 0.2035 | -0.9488 | 0.4343 | |
| HCC1419 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7437.084 | 0.0126 | -0.9999 | 0.4343 | |
| HCC1419 | HER2amp | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7437.084 | 0.0088 | -1.0000 | 0.4343 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7441.084 | 0.9963 | 0.9912 | 0.8431 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7441.084 | 1.0351 | 1.0835 | 0.8431 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7441.084 | 1.0065 | 1.0153 | 0.8431 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7441.084 | 1.0069 | 1.0164 | 0.8431 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7441.084 | 0.7262 | 0.3683 | 0.8431 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7441.084 | 0.0074 | -0.9941 | 0.8431 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7441.084 | 0.0077 | -0.9937 | 0.8431 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7441.084 | 0.0111 | -0.9904 | 0.8431 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7441.084 | 0.0034 | -0.9976 | 0.8431 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7442.085 | 1.0103 | 1.0251 | 0.8237 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7442.085 | 0.9781 | 0.9469 | 0.8237 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7442.085 | 0.9436 | 0.8639 | 0.8237 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7442.085 | 0.6587 | 0.2048 | 0.8237 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7442.085 | 0.3802 | -0.3817 | 0.8237 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7442.085 | 0.0087 | -0.9937 | 0.8237 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7442.085 | 0.0113 | -0.9914 | 0.8237 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7442.085 | 0.0113 | -0.9913 | 0.8237 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7442.085 | 0.0055 | -0.9964 | 0.8237 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7443.084 | 0.9840 | 0.9675 | 0.9878 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7443.084 | 0.9424 | 0.8835 | 0.9878 |