Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | 2-deoxyglucose | 667 | uM | 12989.177 | 0.9269 | 0.6350 | 0.3765 | |||
| MDA-MB-361 | HER2amp | Luminal | 2-deoxyglucose | 3330 | uM | 12989.177 | 0.8271 | 0.2081 | 0.3765 | |||
| MDA-MB-415 | HR+ | Luminal | 2-deoxyglucose | 0.00853 | uM | 12959.177 | 0.9192 | 0.7176 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | 2-deoxyglucose | 0.0427 | uM | 12959.177 | 0.9730 | 0.9037 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | 2-deoxyglucose | 0.213 | uM | 12959.177 | 0.9388 | 0.7843 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | 2-deoxyglucose | 1.07 | uM | 12959.177 | 0.9331 | 0.7650 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | 2-deoxyglucose | 5.33 | uM | 12959.177 | 1.0282 | 1.1029 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | 2-deoxyglucose | 26.7 | uM | 12959.177 | 0.9479 | 0.8157 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | 2-deoxyglucose | 133 | uM | 12959.177 | 0.9861 | 0.9499 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | 2-deoxyglucose | 667 | uM | 12959.177 | 0.9335 | 0.7662 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | 2-deoxyglucose | 3330 | uM | 12959.177 | 0.8207 | 0.3997 | 0.5538 | |||
| MDA-MB-453 | TNBC | Luminal | 2-deoxyglucose | 0.00853 | uM | 12964.177 | 0.8727 | 0.6679 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | 2-deoxyglucose | 0.0427 | uM | 12964.177 | 0.8587 | 0.6321 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | 2-deoxyglucose | 0.213 | uM | 12964.177 | 0.9514 | 0.8714 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | 2-deoxyglucose | 1.07 | uM | 12964.177 | 0.9194 | 0.7879 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | 2-deoxyglucose | 5.33 | uM | 12964.177 | 0.9604 | 0.8949 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | 2-deoxyglucose | 26.7 | uM | 12964.177 | 0.8107 | 0.5116 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | 2-deoxyglucose | 133 | uM | 12964.177 | 0.8440 | 0.5949 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | 2-deoxyglucose | 667 | uM | 12964.177 | 0.7564 | 0.3779 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | 2-deoxyglucose | 3330 | uM | 12964.177 | 0.3919 | -0.4270 | 0.7495 | |||
| MX1 | Unknown | Unknown | 2-deoxyglucose | 0.00853 | uM | 12667.177 | 1.0963 | 1.3376 | 0.5892 | |||
| MX1 | Unknown | Unknown | 2-deoxyglucose | 0.0427 | uM | 12667.177 | 0.8943 | 0.6545 | 0.5892 | |||
| MX1 | Unknown | Unknown | 2-deoxyglucose | 0.213 | uM | 12667.177 | 1.0184 | 1.0629 | 0.5892 | |||
| MX1 | Unknown | Unknown | 2-deoxyglucose | 1.07 | uM | 12667.177 | 0.6889 | 0.0625 | 0.5892 | |||
| MX1 | Unknown | Unknown | 2-deoxyglucose | 5.33 | uM | 12667.177 | 1.0555 | 1.1919 | 0.5892 |