Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | 2-deoxyglucose | 0.00853 | uM | 12662.177 | 0.9713 | 0.9662 | 1.7065 | |||
| MDA-MB-134-VI | HR+ | Luminal | 2-deoxyglucose | 0.0427 | uM | 12662.177 | 0.9520 | 0.9432 | 1.7065 | |||
| MDA-MB-134-VI | HR+ | Luminal | 2-deoxyglucose | 0.213 | uM | 12662.177 | 0.9601 | 0.9529 | 1.7065 | |||
| MDA-MB-134-VI | HR+ | Luminal | 2-deoxyglucose | 1.07 | uM | 12662.177 | 0.9656 | 0.9594 | 1.7065 | |||
| MDA-MB-134-VI | HR+ | Luminal | 2-deoxyglucose | 5.33 | uM | 12662.177 | 0.9591 | 0.9516 | 1.7065 | |||
| MDA-MB-134-VI | HR+ | Luminal | 2-deoxyglucose | 26.7 | uM | 12662.177 | 0.9650 | 0.9587 | 1.7065 | |||
| MDA-MB-134-VI | HR+ | Luminal | 2-deoxyglucose | 133 | uM | 12662.177 | 0.9668 | 0.9608 | 1.7065 | |||
| MDA-MB-134-VI | HR+ | Luminal | 2-deoxyglucose | 667 | uM | 12662.177 | 0.9725 | 0.9676 | 1.7065 | |||
| MDA-MB-134-VI | HR+ | Luminal | 2-deoxyglucose | 3330 | uM | 12662.177 | 0.9975 | 0.9970 | 1.7065 | |||
| MDA-MB-157 | TNBC | Basal B | 2-deoxyglucose | 0.00853 | uM | 12632.177 | 0.9809 | 0.9438 | 0.6753 | |||
| MDA-MB-157 | TNBC | Basal B | 2-deoxyglucose | 0.0427 | uM | 12632.177 | 0.9973 | 0.9920 | 0.6753 | |||
| MDA-MB-157 | TNBC | Basal B | 2-deoxyglucose | 0.213 | uM | 12632.177 | 1.0273 | 1.0814 | 0.6753 | |||
| MDA-MB-157 | TNBC | Basal B | 2-deoxyglucose | 1.07 | uM | 12632.177 | 1.0085 | 1.0253 | 0.6753 | |||
| MDA-MB-157 | TNBC | Basal B | 2-deoxyglucose | 5.33 | uM | 12632.177 | 1.0044 | 1.0131 | 0.6753 | |||
| MDA-MB-157 | TNBC | Basal B | 2-deoxyglucose | 26.7 | uM | 12632.177 | 1.0224 | 1.0668 | 0.6753 | |||
| MDA-MB-157 | TNBC | Basal B | 2-deoxyglucose | 133 | uM | 12632.177 | 0.9856 | 0.9576 | 0.6753 | |||
| MDA-MB-157 | TNBC | Basal B | 2-deoxyglucose | 667 | uM | 12632.177 | 0.8964 | 0.7009 | 0.6753 | |||
| MDA-MB-157 | TNBC | Basal B | 2-deoxyglucose | 3330 | uM | 12632.177 | 0.6022 | -0.0562 | 0.6753 | |||
| MDA-MB-361 | HER2amp | Luminal | 2-deoxyglucose | 0.00853 | uM | 12989.177 | 1.0118 | 1.0635 | 0.3765 | |||
| MDA-MB-361 | HER2amp | Luminal | 2-deoxyglucose | 0.0427 | uM | 12989.177 | 0.8424 | 0.2684 | 0.3765 | |||
| MDA-MB-361 | HER2amp | Luminal | 2-deoxyglucose | 0.213 | uM | 12989.177 | 1.0421 | 1.2312 | 0.3765 | |||
| MDA-MB-361 | HER2amp | Luminal | 2-deoxyglucose | 1.07 | uM | 12989.177 | 0.7334 | -0.1223 | 0.3765 | |||
| MDA-MB-361 | HER2amp | Luminal | 2-deoxyglucose | 5.33 | uM | 12989.177 | 1.0073 | 1.0391 | 0.3765 | |||
| MDA-MB-361 | HER2amp | Luminal | 2-deoxyglucose | 26.7 | uM | 12989.177 | 1.0156 | 1.0841 | 0.3765 | |||
| MDA-MB-361 | HER2amp | Luminal | 2-deoxyglucose | 133 | uM | 12989.177 | 1.0306 | 1.1667 | 0.3765 |