Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-231 | 0 | uM | 2 | 156.25 | 73.46 | 216.00 | 162.32 | 1.3307 | 1.5675 | |
BT-20 | 0 | uM | 3 | 5000.00 | 2450.33 | 8516.00 | 6399.50 | 1.3307 | 1.4583 | |
MDA-MB-231 | Etoposide | 0.01 | uM | 2 | 625.00 | 269.08 | 986.00 | 741.00 | 1.3306 | 1.4318 |
MDA-MB-231 | PLX-4720 | 3.1623 | uM | 2 | 625.00 | 269.08 | 986.00 | 741.00 | 1.3306 | 1.4318 |
SK-BR-3 | Etoposide | 0.1 | uM | 5 | 312.50 | 138.75 | 322.00 | 242.00 | 1.3306 | 1.8549 |
Hs 578T | 0 | uM | 10 | 312.50 | 125.09 | 320.00 | 240.50 | 1.3306 | 1.7074 | |
MCF 10A | Nilotinib | 0.01 | uM | 5 | 156.25 | 36.94 | 2522.00 | 1895.50 | 1.3305 | 1.1031 |
MCF7 | Erlotinib | 0.1 | uM | 10 | 625.00 | 172.23 | 611.00 | 459.25 | 1.3304 | 1.4471 |
MDA-MB-231 | Methotrexate | 1 | uM | 2 | 312.50 | 142.67 | 603.00 | 453.25 | 1.3304 | 1.3734 |
BT-20 | NVP-TAE684 | 0.1 | uM | 3 | 156.25 | 49.48 | 146.00 | 109.75 | 1.3303 | 1.5637 |
BT-20 | PLX-4720 | 0.31623 | uM | 3 | 156.25 | 49.48 | 146.00 | 109.75 | 1.3303 | 1.5637 |
BT-20 | 0 | uM | 3 | 156.25 | 49.48 | 133.00 | 100.00 | 1.3300 | 1.6487 | |
BT-20 | 0 | uM | 8 | 156.25 | 28.44 | 133.00 | 100.00 | 1.3300 | 1.3405 | |
BT-20 | PLX-4720 | 0.031623 | uM | 3 | 625.00 | 278.42 | 932.00 | 700.75 | 1.3300 | 1.4776 |
MDA-MB-231 | 0 | uM | 2 | 312.50 | 142.67 | 525.00 | 394.75 | 1.3300 | 1.4287 | |
BT-20 | Erlotinib | 0.0033113 | uM | 8 | 156.25 | 28.44 | 133.00 | 100.00 | 1.3300 | 1.3405 |
BT-20 | Nilotinib | 0.031623 | uM | 3 | 625.00 | 278.42 | 932.00 | 700.75 | 1.3300 | 1.4776 |
MCF 10A | NVP-TAE684 | 0.01 | uM | 6 | 312.50 | 97.42 | 2964.00 | 2228.75 | 1.3299 | 1.1303 |
SK-BR-3 | NVP-TAE684 | 0.0033113 | uM | 4 | 625.00 | 368.38 | 774.00 | 582.00 | 1.3299 | 2.0809 |
MCF7 | 0 | uM | 10 | 156.25 | 46.73 | 126.00 | 94.75 | 1.3298 | 1.6449 | |
MCF 10A | 0 | uM | 2 | 5000.00 | 3410.67 | 8591.00 | 6460.50 | 1.3298 | 1.7248 | |
MCF7 | Linsitinib | 0.031623 | uM | 10 | 156.25 | 46.73 | 126.00 | 94.75 | 1.3298 | 1.6449 |
Hs 578T | PLX-4720 | 3.1623 | uM | 1 | 312.50 | 222.17 | 852.00 | 640.75 | 1.3297 | 1.4100 |
Hs 578T | Nilotinib | 0.31623 | uM | 1 | 156.25 | 76.08 | 247.00 | 185.75 | 1.3297 | 1.4954 |
BT-20 | PLX-4720 | 0.31623 | uM | 5 | 625.00 | 303.96 | 981.00 | 737.75 | 1.3297 | 1.4990 |