PF-3758309 KiNativ -- single dose experiment - Dataset (ID:20254)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| PF-3758309 | THP-1 | ACK | TVSVAVKCLKPDVLSQPEAMDDFIR | Lys1 | 1.9 | 1 | uM |
| PF-3758309 | THP-1 | AMPKa1,AMPKa2 | VAVKILNR | Lys1 | 97.6 | 1 | uM |
| PF-3758309 | THP-1 | AMPKa1,AMPKa2 | DLKPENVLLDAHMNAK | Lys2 | 96.4 | 1 | uM |
| PF-3758309 | THP-1 | ATM | QLVKGRDDLRQDAVMQQVFQMCNTLLQR | ATP | -11.3 | 1 | uM |
| PF-3758309 | THP-1 | ATR | FYIMMCKPK | ATP | -17.7 | 1 | uM |
| PF-3758309 | THP-1 | AurA | FILALKVLFK | Lys1 | 25.3 | 1 | uM |
| PF-3758309 | THP-1 | BRAF | DLKSNNIFLHEDLTVK | Lys2 | -5.4 | 1 | uM |
| PF-3758309 | THP-1 | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | -2.7 | 1 | uM |
| PF-3758309 | THP-1 | CaMK1a | LVAIKCIAK | Lys1 | 41.7 | 1 | uM |
| PF-3758309 | THP-1 | CAMK1D | LFAVKCIPK | Lys1 | 73.7 | 1 | uM |
| PF-3758309 | THP-1 | CaMK2a,CaMK2b,CaMK2d,CaMK2g | DLKPENLLLASK | Lys2 | 79.9 | 1 | uM |
| PF-3758309 | THP-1 | KCC2D | IPTGQEYAAKIINTK | Lys1 | 89.8 | 1 | uM |
| PF-3758309 | THP-1 | CaMK2g | TSTQEYAAKIINTK | Lys1 | 89.3 | 1 | uM |
| PF-3758309 | THP-1 | CaMKK2 | LAYNENDNTYYAMKVLSK | Lys1 | 61.8 | 1 | uM |
| PF-3758309 | THP-1 | CDK20 | DLKPANLLISASGQLK | Lys2 | 7.1 | 1 | uM |
| PF-3758309 | THP-1 | CDC2 | DLKPQNLLIDDKGTIK | Lys2 | -0.9 | 1 | uM |
| PF-3758309 | THP-1 | CDK11,CDK8 | DLKPANILVMGEGPER | Lys2 | -29.4 | 1 | uM |
| PF-3758309 | THP-1 | CDK2 | NKLTGEVVALKK | Lys1 | -9.0 | 1 | uM |
| PF-3758309 | THP-1 | CDK2 | DLKPQNLLINTEGAIK | Lys2 | 2.8 | 1 | uM |
| PF-3758309 | THP-1 | CDK4 | DLKPENILVTSGGTVK | Lys2 | -8.8 | 1 | uM |
| PF-3758309 | THP-1 | CDK5 | NRETHEIVALKR | Lys1 | 7.6 | 1 | uM |
| PF-3758309 | THP-1 | CDK5 | DLKPQNLLINR | Lys2 | -31.5 | 1 | uM |
| PF-3758309 | THP-1 | CDK6 | DLKPQNILVTSSGQIK | Lys2 | -6.4 | 1 | uM |
| PF-3758309 | THP-1 | CDK7 | DLKPNNLLLDENGVLK | Lys2 | 96.5 | 1 | uM |
| PF-3758309 | THP-1 | CDK9 | DMKAANVLITR | Lys2 | -5.6 | 1 | uM |