PF-3758309 KiNativ -- single dose experiment - Dataset (ID:20254)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| PF-3758309 | THP-1 | PIK3CD | VNWLAHNVSKDNRQ | ATP | -0.4 | 1 | uM |
| PF-3758309 | THP-1 | CDC2 | DLKPQNLLIDDKGTIK | Lys2 | -0.9 | 1 | uM |
| PF-3758309 | THP-1 | FYV1 | GGKSGAAFYATEDDRFILK | ATP | -0.9 | 1 | uM |
| PF-3758309 | THP-1 | Wnk1,Wnk2,Wnk3 | DLKCDNIFITGPTGSVK | Lys2 | 0.9 | 1 | uM |
| PF-3758309 | THP-1 | JNK1,JNK2,JNK3 | DLKPSNIVVK | Lys2 | 1.0 | 1 | uM |
| PF-3758309 | THP-1 | M3K2,MAP3K3 | DIKGANILR | Lys2 | 10.7 | 1 | uM |
| PF-3758309 | THP-1 | MAP2K4 | MVHKPSGQIMAVKR | Lys1 | -10.8 | 1 | uM |
| PF-3758309 | THP-1 | p38a | DLKPSNLAVNEDCELK | Lys2 | 1.1 | 1 | uM |
| PF-3758309 | THP-1 | ATM | QLVKGRDDLRQDAVMQQVFQMCNTLLQR | ATP | -11.3 | 1 | uM |
| PF-3758309 | THP-1 | PRPK | FLSGLELVKQGAEAR | ATP Loop | 12.4 | 1 | uM |
| PF-3758309 | THP-1 | CSK | VSDFGLTKEASSTQDTGKLPVK | Activation Loop | 12.7 | 1 | uM |
| PF-3758309 | THP-1 | STLK6 | HTPTGTLVTIKITNLENCNEER | Lys1 | -12.8 | 1 | uM |
| PF-3758309 | THP-1 | NEK7 | AACLLDGVPVALKK | Lys1 | -13.2 | 1 | uM |
| PF-3758309 | THP-1 | RIPK3 | DLKPSNVLLDPELHVK | Lys2 | -14.0 | 1 | uM |
| PF-3758309 | THP-1 | MP2K7 | DVKPSNILLDER | Lys2 | 14.7 | 1 | uM |
| PF-3758309 | THP-1 | HPK1 | DKVSGDLVALKMVK | Lys1 | 15.1 | 1 | uM |
| PF-3758309 | THP-1 | GCK | DTVTSELAAVKIVK | Lys1 | 1.6 | 1 | uM |
| PF-3758309 | THP-1 | SGK3 | FYAVKVLQK | Lys1 | -16.1 | 1 | uM |
| PF-3758309 | THP-1 | MAP2K6 | HVPSGQIMAVKR | Lys1 | -16.4 | 1 | uM |
| PF-3758309 | THP-1 | NEK3 | SKNIFLTQNGK | Activation Loop | -1.7 | 1 | uM |
| PF-3758309 | THP-1 | SLK | DLKAGNILFTLDGDIK | Lys2 | 17.6 | 1 | uM |
| PF-3758309 | THP-1 | ATR | FYIMMCKPK | ATP | -17.7 | 1 | uM |
| PF-3758309 | THP-1 | MAP2K5 | DVKPSNMLVNTR | Lys2 | -18.2 | 1 | uM |
| PF-3758309 | THP-1 | ACK | TVSVAVKCLKPDVLSQPEAMDDFIR | Lys1 | 1.9 | 1 | uM |
| PF-3758309 | THP-1 | PI42C | TLVIKEVSSEDIADMHSNLSNYHQYIVK | ATP | -20.7 | 1 | uM |