PF-3758309 KiNativ -- single dose experiment - Dataset (ID:20254)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| PF-3758309 | THP-1 | FAK2 | YIEDEDYYKASVTR | Activation Loop | 63.9 | 1 | uM |
| PF-3758309 | THP-1 | MER,TYRO3 | KIYSGDYYR | Activation Loop | 74.2 | 1 | uM |
| PF-3758309 | THP-1 | NEK3 | SKNIFLTQNGK | Activation Loop | -1.7 | 1 | uM |
| PF-3758309 | THP-1 | Wnk1,Wnk2,Wnk4 | IGDLGLATLKR | Activation Loop | -3.8 | 1 | uM |
| PF-3758309 | THP-1 | FGR | LIKDDEYNPCQGSKFPIK | Activation Loop | 6.8 | 1 | uM |
| PF-3758309 | THP-1 | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | -2.7 | 1 | uM |
| PF-3758309 | THP-1 | CSK | VSDFGLTKEASSTQDTGKLPVK | Activation Loop | 12.7 | 1 | uM |
| PF-3758309 | THP-1 | PIK3CG | KKPLWLEFK | ATP | 2.3 | 1 | uM |
| PF-3758309 | THP-1 | PIP4K2A | AKELPTLKDNDFINEGQK | ATP | 4.1 | 1 | uM |
| PF-3758309 | THP-1 | PIK3CB | VFGEDSVGVIFKNGDDLR | ATP | 7.1 | 1 | uM |
| PF-3758309 | THP-1 | PI42C | TLVIKEVSSEDIADMHSNLSNYHQYIVK | ATP | -20.7 | 1 | uM |
| PF-3758309 | THP-1 | PIK3CD | VNWLAHNVSKDNRQ | ATP | -0.4 | 1 | uM |
| PF-3758309 | THP-1 | FYV1 | GGKSGAAFYATEDDRFILK | ATP | -0.9 | 1 | uM |
| PF-3758309 | THP-1 | eEF2K | YIKYNSNSGFVR | ATP | -2.2 | 1 | uM |
| PF-3758309 | THP-1 | ATM | QLVKGRDDLRQDAVMQQVFQMCNTLLQR | ATP | -11.3 | 1 | uM |
| PF-3758309 | THP-1 | DNAPK | EHPFLVKGGEDLR | ATP | 9.2 | 1 | uM |
| PF-3758309 | THP-1 | FRAP1 | IQSIAPSLQVITSKQRPR | ATP | 9.4 | 1 | uM |
| PF-3758309 | THP-1 | ATR | FYIMMCKPK | ATP | -17.7 | 1 | uM |
| PF-3758309 | THP-1 | PRPK | FLSGLELVKQGAEAR | ATP Loop | 12.4 | 1 | uM |
| PF-3758309 | THP-1 | ACK | TVSVAVKCLKPDVLSQPEAMDDFIR | Lys1 | 1.9 | 1 | uM |
| PF-3758309 | THP-1 | CaMKK2 | LAYNENDNTYYAMKVLSK | Lys1 | 61.8 | 1 | uM |
| PF-3758309 | THP-1 | GCK | DTVTSELAAVKIVK | Lys1 | 1.6 | 1 | uM |
| PF-3758309 | THP-1 | CaMK2g | TSTQEYAAKIINTK | Lys1 | 89.3 | 1 | uM |
| PF-3758309 | THP-1 | AurA | FILALKVLFK | Lys1 | 25.3 | 1 | uM |
| PF-3758309 | THP-1 | KCC2D | IPTGQEYAAKIINTK | Lys1 | 89.8 | 1 | uM |