LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MCF7 PF477736
10
uM
LJP5
 0.2989 0.0255 0.0527 0.0218
MCF7 LDN-193189
0.04
uM
LJP5
 1.0721 0.0251 1.0757 0.0273
MCF7 LDN-193189
0.12
uM
LJP5
 1.0002 0.0417 1.0030 0.0436
MCF7 LDN-193189
0.37
uM
LJP5
 1.0089 0.0382 1.0108 0.0414
MCF7 LDN-193189
1.11
uM
LJP5
 0.8807 0.0198 0.8683 0.0257
MCF7 LDN-193189
3.33
uM
LJP5
 0.4350 0.1037 0.2581 0.1932
MCF7 LDN-193189
10
uM
LJP5
 0.1151 0.0128 -0.3681 0.0113
MCF7 PF431396
0.04
uM
LJP5
 0.7730 0.0225 0.7415 0.0374
MCF7 PF431396
0.12
uM
LJP5
 0.5632 0.0283 0.4706 0.0587
MCF7 PF431396
0.37
uM
LJP5
 0.3736 0.0114 0.1842 0.0448
MCF7 PF431396
1.11
uM
LJP5
 0.3043 0.0197 0.0628 0.0148
MCF7 PF431396
3.33
uM
LJP5
 0.2594 0.0138 -0.0235 0.0217
MCF7 PF431396
10
uM
LJP5
 0.1472 0.0184 -0.2798 0.0176
MCF7 Celastrol
0.04
uM
LJP6
 1.0937 0.0252 1.1012 0.0245
MCF7 Celastrol
0.12
uM
LJP6
 0.9993 0.0151 0.9979 0.0158
MCF7 Celastrol
0.37
uM
LJP6
 0.6153 0.0554 0.5204 0.0901
MCF7 Celastrol
1.11
uM
LJP6
 0.3521 0.0177 0.1173 0.0582
MCF7 Celastrol
3.33
uM
LJP6
 0.2332 0.0145 -0.1114 0.0522
MCF7 Celastrol
10
uM
LJP6
 0.1938 0.0369 -0.2046 0.0903
MCF7 SU11274
0.04
uM
LJP5
 1.0994 0.0231 1.1035 0.0264
MCF7 SU11274
0.12
uM
LJP5
 1.0445 0.0391 1.0473 0.0436
MCF7 SU11274
0.37
uM
LJP5
 1.0118 0.0378 1.0123 0.0419
MCF7 SU11274
1.11
uM
LJP5
 0.8694 0.0231 0.8578 0.0217
MCF7 SU11274
3.33
uM
LJP5
 0.7485 0.0110 0.7120 0.0262
MCF7 SU11274
10
uM
LJP5
 0.3240 0.0244 0.0989 0.0265