LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF7 | Radicicol | 3.33 | uM | LJP6 | 0.3431 | 0.0236 | 0.1035 | 0.0132 |
| MCF7 | Radicicol | 10 | uM | LJP5 | 0.2315 | 0.0064 | -0.0803 | 0.0241 |
| MCF7 | Radicicol | 10 | uM | LJP6 | 0.2321 | 0.0040 | -0.1121 | 0.0242 |
| MCF7 | Withaferin A | 0.04 | uM | LJP5 | 1.0267 | 0.0356 | 1.0291 | 0.0393 |
| MCF7 | Withaferin A | 0.04 | uM | LJP6 | 1.0035 | 0.0247 | 1.0009 | 0.0277 |
| MCF7 | Withaferin A | 0.12 | uM | LJP5 | 0.9552 | 0.0450 | 0.9530 | 0.0493 |
| MCF7 | Withaferin A | 0.12 | uM | LJP6 | 0.8824 | 0.0377 | 0.8607 | 0.0483 |
| MCF7 | Withaferin A | 0.37 | uM | LJP5 | 0.4448 | 0.0242 | 0.2969 | 0.0634 |
| MCF7 | Withaferin A | 0.37 | uM | LJP6 | 0.4423 | 0.0168 | 0.2688 | 0.0511 |
| MCF7 | Withaferin A | 1.11 | uM | LJP5 | 0.3298 | 0.0200 | 0.1098 | 0.0211 |
| MCF7 | Withaferin A | 1.11 | uM | LJP6 | 0.3228 | 0.0074 | 0.0667 | 0.0162 |
| MCF7 | Withaferin A | 3.33 | uM | LJP5 | 0.1814 | 0.0340 | -0.1995 | 0.0861 |
| MCF7 | Withaferin A | 3.33 | uM | LJP6 | 0.1982 | 0.0336 | -0.1921 | 0.0809 |
| MCF7 | Withaferin A | 10 | uM | LJP5 | 0.2132 | 0.0243 | -0.1227 | 0.0573 |
| MCF7 | Withaferin A | 10 | uM | LJP6 | 0.2123 | 0.0257 | -0.1584 | 0.0675 |
| SK-BR-3 | Seliciclib | 0.04 | uM | LJP5 | 1.0292 | 0.0378 | 1.0436 | 0.0539 |
| SK-BR-3 | Seliciclib | 0.12 | uM | LJP5 | 1.0266 | 0.0181 | 1.0411 | 0.0257 |
| SK-BR-3 | Seliciclib | 0.37 | uM | LJP5 | 0.9839 | 0.0359 | 0.9793 | 0.0491 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 0.8990 | 0.0198 | 0.8522 | 0.0246 |
| SK-BR-3 | Seliciclib | 3.33 | uM | LJP5 | 0.7857 | 0.0193 | 0.6774 | 0.0131 |
| SK-BR-3 | Seliciclib | 10 | uM | LJP5 | 0.4714 | 0.0484 | 0.1464 | 0.1021 |
| SK-BR-3 | AT-7519 | 0.04 | uM | LJP6 | 0.8063 | 0.1043 | 0.7174 | 0.1376 |
| SK-BR-3 | AT-7519 | 0.12 | uM | LJP6 | 0.4778 | 0.0707 | 0.1403 | 0.0626 |
| SK-BR-3 | AT-7519 | 0.37 | uM | LJP6 | 0.3511 | 0.0348 | -0.1037 | 0.0430 |
| SK-BR-3 | AT-7519 | 1.11 | uM | LJP6 | 0.2620 | 0.0279 | -0.2840 | 0.0893 |