LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
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SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 1.0239 | 0.0063 | 1.0368 | 0.0050 |
SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 1.0290 | 0.0065 | 1.0439 | 0.0055 |
SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 1.0095 | 0.0206 | 1.0196 | 0.0303 |
SK-BR-3 | Selumetinib | 3.33 | uM | LJP6 | 1.0164 | 0.0154 | 1.0214 | 0.0188 |
SK-BR-3 | Selumetinib | 10 | uM | LJP6 | 0.9817 | 0.0125 | 0.9687 | 0.0198 |
SK-BR-3 | MK2206 | 0.04 | uM | LJP6 | 0.8419 | 0.0555 | 0.7608 | 0.0710 |
SK-BR-3 | MK2206 | 0.12 | uM | LJP6 | 0.7478 | 0.0387 | 0.6035 | 0.0483 |
SK-BR-3 | MK2206 | 0.37 | uM | LJP6 | 0.6777 | 0.0177 | 0.4844 | 0.0344 |
SK-BR-3 | MK2206 | 1.11 | uM | LJP6 | 0.6441 | 0.0255 | 0.4294 | 0.0276 |
SK-BR-3 | MK2206 | 3.33 | uM | LJP6 | 0.5598 | 0.0179 | 0.2827 | 0.0340 |
SK-BR-3 | MK2206 | 10 | uM | LJP6 | 0.3704 | 0.0345 | -0.0652 | 0.0087 |
SK-BR-3 | AZD-6482 | 0.04 | uM | LJP5 | 0.9919 | 0.0049 | 0.9875 | 0.0072 |
SK-BR-3 | AZD-6482 | 0.12 | uM | LJP5 | 0.9399 | 0.0304 | 0.9154 | 0.0363 |
SK-BR-3 | AZD-6482 | 0.37 | uM | LJP5 | 0.9981 | 0.0322 | 1.0002 | 0.0444 |
SK-BR-3 | AZD-6482 | 1.11 | uM | LJP5 | 0.9080 | 0.0357 | 0.8698 | 0.0413 |
SK-BR-3 | AZD-6482 | 3.33 | uM | LJP5 | 0.6241 | 0.0054 | 0.4043 | 0.0453 |
SK-BR-3 | AZD-6482 | 10 | uM | LJP5 | 0.3372 | 0.0318 | -0.1069 | 0.1198 |
SK-BR-3 | NU7441 | 0.04 | uM | LJP5 | 1.0313 | 0.0147 | 1.0443 | 0.0211 |
SK-BR-3 | NU7441 | 0.12 | uM | LJP5 | 0.9688 | 0.0160 | 0.9568 | 0.0199 |
SK-BR-3 | NU7441 | 0.37 | uM | LJP5 | 0.9125 | 0.0193 | 0.8675 | 0.0354 |
SK-BR-3 | NU7441 | 1.11 | uM | LJP5 | 0.8170 | 0.0510 | 0.7144 | 0.0879 |
SK-BR-3 | NU7441 | 3.33 | uM | LJP5 | 0.7655 | 0.0293 | 0.6441 | 0.0475 |
SK-BR-3 | NU7441 | 10 | uM | LJP5 | 0.4957 | 0.0506 | 0.1986 | 0.0443 |
SK-BR-3 | OSI-027 | 0.04 | uM | LJP6 | 0.8399 | 0.0580 | 0.7599 | 0.0660 |
SK-BR-3 | OSI-027 | 0.12 | uM | LJP6 | 0.5800 | 0.0505 | 0.3216 | 0.0390 |