LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MCF7 Canertinib
0.04
uM
LJP6
0.9922 0.0026 0.9894 0.0033
MCF7 Canertinib
0.12
uM
LJP6
0.8985 0.0177 0.8836 0.0201
MCF7 Canertinib
0.37
uM
LJP6
0.8298 0.0214 0.8006 0.0308
MCF7 Canertinib
1.11
uM
LJP6
0.7251 0.0276 0.6700 0.0360
MCF7 Canertinib
3.33
uM
LJP6
0.6034 0.0454 0.5047 0.0754
MCF7 Canertinib
10
uM
LJP6
0.1277 0.0225 -0.3673 0.0529
MCF7 NVP-AEW541
0.04
uM
LJP5
0.9781 0.0204 0.9752 0.0230
MCF7 NVP-AEW541
0.12
uM
LJP5
0.8553 0.0570 0.8344 0.0716
MCF7 NVP-AEW541
0.37
uM
LJP5
0.5759 0.0109 0.4899 0.0224
MCF7 NVP-AEW541
1.11
uM
LJP5
0.5152 0.0061 0.4052 0.0325
MCF7 NVP-AEW541
3.33
uM
LJP5
0.5082 0.0219 0.3935 0.0523
MCF7 NVP-AEW541
10
uM
LJP5
0.2383 0.0134 -0.0685 0.0581
MCF7 PHA-665752
0.04
uM
LJP5
1.0594 0.0104 1.0613 0.0068
MCF7 PHA-665752
0.12
uM
LJP5
1.0597 0.0392 1.0611 0.0422
MCF7 PHA-665752
0.37
uM
LJP5
1.0483 0.0292 1.0488 0.0296
MCF7 PHA-665752
1.11
uM
LJP5
1.0122 0.0352 1.0087 0.0340
MCF7 PHA-665752
3.33
uM
LJP5
0.9304 0.0244 0.9233 0.0299
MCF7 PHA-665752
10
uM
LJP5
0.7171 0.0703 0.6655 0.0979
MCF7 PI103
0.04
uM
LJP6
0.7581 0.0587 0.7097 0.0795
MCF7 PI103
0.12
uM
LJP6
0.5167 0.0564 0.3789 0.0907
MCF7 PI103
0.37
uM
LJP6
0.3249 0.0277 0.0687 0.0466
MCF7 PI103
1.11
uM
LJP6
0.2640 0.0191 -0.0473 0.0295
MCF7 PI103
3.33
uM
LJP6
0.2488 0.0172 -0.0779 0.0364
MCF7 PI103
10
uM
LJP6
0.2142 0.0253 -0.1534 0.0602
MCF7 Dovitinib
0.04
uM
LJP5
0.9044 0.0277 0.8977 0.0269