LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MCF7 PD184352
0.37
uM
LJP5
0.7522 0.0256 0.7183 0.0344
MCF7 PD184352
1.11
uM
LJP5
0.6923 0.0391 0.6458 0.0426
MCF7 PD184352
3.33
uM
LJP5
0.6369 0.0224 0.5743 0.0196
MCF7 PD184352
10
uM
LJP5
0.4740 0.0060 0.3444 0.0214
MCF7 PLX-4720
0.04
uM
LJP5
1.0375 0.0413 1.0376 0.0451
MCF7 PLX-4720
0.12
uM
LJP5
0.9504 0.0117 0.9445 0.0160
MCF7 PLX-4720
0.37
uM
LJP5
1.0182 0.0276 1.0161 0.0282
MCF7 PLX-4720
1.11
uM
LJP5
0.9930 0.0109 0.9910 0.0116
MCF7 PLX-4720
3.33
uM
LJP5
0.8689 0.0446 0.8514 0.0561
MCF7 PLX-4720
10
uM
LJP5
0.5849 0.0720 0.4995 0.0918
MCF7 Lapatinib
0.04
uM
LJP6
0.8345 0.0516 0.8035 0.0697
MCF7 Lapatinib
0.12
uM
LJP6
0.8943 0.0620 0.8718 0.0746
MCF7 Lapatinib
0.37
uM
LJP6
0.9576 0.0372 0.9474 0.0426
MCF7 Lapatinib
1.11
uM
LJP6
0.9478 0.0457 0.9365 0.0529
MCF7 Lapatinib
3.33
uM
LJP6
0.9350 0.0245 0.9261 0.0291
MCF7 Lapatinib
10
uM
LJP6
0.4779 0.0477 0.3214 0.0804
MCF7 Sirolimus
0.04
uM
LJP6
0.5982 0.0299 0.5019 0.0434
MCF7 Sirolimus
0.12
uM
LJP6
0.5980 0.0287 0.5022 0.0402
MCF7 Sirolimus
0.37
uM
LJP6
0.5865 0.0160 0.4859 0.0276
MCF7 Sirolimus
1.11
uM
LJP6
0.5894 0.0330 0.4896 0.0463
MCF7 Sirolimus
3.33
uM
LJP6
0.5929 0.0168 0.4953 0.0278
MCF7 Sirolimus
10
uM
LJP6
0.5661 0.0396 0.4564 0.0556
MCF7 ZSTK474
0.04
uM
LJP6
0.7248 0.0815 0.6639 0.1149
MCF7 ZSTK474
0.12
uM
LJP6
0.5124 0.0600 0.3697 0.1057
MCF7 ZSTK474
0.37
uM
LJP6
0.3629 0.0118 0.1381 0.0276