LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MCF7 | BI-2536 | 0.12 | uM | LJP6 | 0.3188 | 0.0211 | 0.0593 | 0.0097 |
MCF7 | BI-2536 | 0.37 | uM | LJP6 | 0.3170 | 0.0279 | 0.0551 | 0.0254 |
MCF7 | BI-2536 | 1.11 | uM | LJP6 | 0.3140 | 0.0329 | 0.0492 | 0.0381 |
MCF7 | BI-2536 | 3.33 | uM | LJP6 | 0.2997 | 0.0286 | 0.0223 | 0.0272 |
MCF7 | BI-2536 | 10 | uM | LJP6 | 0.1976 | 0.0183 | -0.1905 | 0.0220 |
MCF7 | A443654 | 0.04 | uM | LJP6 | 0.2819 | 0.0287 | -0.0127 | 0.0503 |
MCF7 | A443654 | 0.12 | uM | LJP6 | 0.2178 | 0.0141 | -0.1433 | 0.0147 |
MCF7 | A443654 | 0.37 | uM | LJP6 | 0.1638 | 0.0243 | -0.2722 | 0.0675 |
MCF7 | A443654 | 1.11 | uM | LJP6 | 0.1663 | 0.0145 | -0.2631 | 0.0264 |
MCF7 | A443654 | 3.33 | uM | LJP6 | 0.1503 | 0.0044 | -0.3031 | 0.0325 |
MCF7 | A443654 | 10 | uM | LJP6 | 0.1284 | 0.0280 | -0.3680 | 0.0628 |
MCF7 | SB590885 | 0.04 | uM | LJP5 | 0.9338 | 0.0462 | 0.9285 | 0.0500 |
MCF7 | SB590885 | 0.12 | uM | LJP5 | 0.9717 | 0.0263 | 0.9702 | 0.0257 |
MCF7 | SB590885 | 0.37 | uM | LJP5 | 1.0117 | 0.0375 | 1.0127 | 0.0404 |
MCF7 | SB590885 | 1.11 | uM | LJP5 | 1.0714 | 0.0439 | 1.0737 | 0.0480 |
MCF7 | SB590885 | 3.33 | uM | LJP5 | 1.0569 | 0.0442 | 1.0565 | 0.0461 |
MCF7 | SB590885 | 10 | uM | LJP5 | 0.4919 | 0.1997 | 0.2761 | 0.3688 |
MCF7 | Pictilisib | 0.04 | uM | LJP6 | 0.4825 | 0.0311 | 0.3312 | 0.0581 |
MCF7 | Pictilisib | 0.12 | uM | LJP6 | 0.3857 | 0.0140 | 0.1763 | 0.0455 |
MCF7 | Pictilisib | 0.37 | uM | LJP6 | 0.2977 | 0.0026 | 0.0196 | 0.0270 |
MCF7 | Pictilisib | 1.11 | uM | LJP6 | 0.2853 | 0.0159 | -0.0042 | 0.0041 |
MCF7 | Pictilisib | 3.33 | uM | LJP6 | 0.2694 | 0.0171 | -0.0358 | 0.0076 |
MCF7 | Pictilisib | 10 | uM | LJP6 | 0.2476 | 0.0232 | -0.0810 | 0.0397 |
MCF7 | PD184352 | 0.04 | uM | LJP5 | 0.9301 | 0.0783 | 0.9147 | 0.0895 |
MCF7 | PD184352 | 0.12 | uM | LJP5 | 0.8331 | 0.0608 | 0.8105 | 0.0772 |