LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | A443654 | 10 | uM | LJP6 | 72 | hr | 1401 | 931 | 4168 | 0.2232 | -0.2301 |
| SK-BR-3 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4804 | 4245 | 1.1362 | 1.1710 |
| SK-BR-3 | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4604 | 4245 | 1.0840 | 1.1029 |
| SK-BR-3 | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4685 | 4245 | 1.1047 | 1.1302 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4714 | 4245 | 1.1121 | 1.1397 |
| SK-BR-3 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4570 | 4245 | 1.0746 | 1.0901 |
| SK-BR-3 | SB590885 | 10 | uM | LJP5 | 72 | hr | 1401 | 840 | 4245 | 0.1990 | -0.2743 |
| SK-BR-3 | Pictilisib | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2664 | 4168 | 0.6400 | 0.5051 |
| SK-BR-3 | Pictilisib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 2262 | 4168 | 0.5425 | 0.3551 |
| SK-BR-3 | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1864 | 4168 | 0.4475 | 0.1990 |
| SK-BR-3 | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1695 | 4168 | 0.4069 | 0.1286 |
| SK-BR-3 | Pictilisib | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1576 | 4168 | 0.3780 | 0.0772 |
| SK-BR-3 | Pictilisib | 10 | uM | LJP6 | 72 | hr | 1401 | 1496 | 4168 | 0.3588 | 0.0417 |
| SK-BR-3 | PD184352 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4357 | 4245 | 1.0259 | 1.0315 |
| SK-BR-3 | PD184352 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4570 | 4245 | 1.0784 | 1.0989 |
| SK-BR-3 | PD184352 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4471 | 4245 | 1.0526 | 1.0647 |
| SK-BR-3 | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4402 | 4245 | 1.0376 | 1.0476 |
| SK-BR-3 | PD184352 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4447 | 4245 | 1.0482 | 1.0601 |
| SK-BR-3 | PD184352 | 10 | uM | LJP5 | 72 | hr | 1401 | 3210 | 4245 | 0.7575 | 0.6813 |
| SK-BR-3 | PLX-4720 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4213 | 4245 | 0.9946 | 0.9951 |
| SK-BR-3 | PLX-4720 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4352 | 4245 | 1.0239 | 1.0280 |
| SK-BR-3 | PLX-4720 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3863 | 4245 | 0.9070 | 0.8753 |
| SK-BR-3 | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4204 | 4245 | 0.9901 | 0.9875 |
| SK-BR-3 | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3476 | 4245 | 0.8069 | 0.7202 |
| SK-BR-3 | PLX-4720 | 10 | uM | LJP5 | 72 | hr | 1401 | 2797 | 4245 | 0.6511 | 0.5112 |