LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Sigma A6730 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3054 | 4245 | 0.7192 | 0.6261 |
| SK-BR-3 | Sigma A6730 | 10 | uM | LJP5 | 72 | hr | 1401 | 2259 | 4245 | 0.5317 | 0.3451 |
| SK-BR-3 | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4737 | 4245 | 1.1201 | 1.1513 |
| SK-BR-3 | WH-4-025 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4448 | 4245 | 1.0518 | 1.0678 |
| SK-BR-3 | WH-4-025 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3382 | 4245 | 0.8013 | 0.6736 |
| SK-BR-3 | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4406 | 4245 | 1.0452 | 1.0604 |
| SK-BR-3 | WH-4-025 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4040 | 4245 | 0.9601 | 0.9525 |
| SK-BR-3 | WH-4-025 | 10 | uM | LJP5 | 72 | hr | 1401 | 1181 | 4245 | 0.2807 | -0.1002 |
| SK-BR-3 | R406 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3936 | 4168 | 0.9448 | 0.9292 |
| SK-BR-3 | R406 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 4060 | 4168 | 0.9743 | 0.9673 |
| SK-BR-3 | R406 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 4112 | 4168 | 0.9874 | 0.9843 |
| SK-BR-3 | R406 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 4454 | 4168 | 1.0686 | 1.0863 |
| SK-BR-3 | R406 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 4528 | 4168 | 1.0876 | 1.1099 |
| SK-BR-3 | R406 | 10 | uM | LJP6 | 72 | hr | 1401 | 3034 | 4168 | 0.7279 | 0.6342 |
| SK-BR-3 | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1352 | 4168 | 0.3243 | -0.0230 |
| SK-BR-3 | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1253 | 4168 | 0.3010 | -0.0683 |
| SK-BR-3 | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1380 | 4168 | 0.3313 | -0.0099 |
| SK-BR-3 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1232 | 4168 | 0.2956 | -0.0789 |
| SK-BR-3 | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1282 | 4168 | 0.3077 | -0.0551 |
| SK-BR-3 | BI-2536 | 10 | uM | LJP6 | 72 | hr | 1401 | 1208 | 4168 | 0.2897 | -0.0928 |
| SK-BR-3 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1914 | 4168 | 0.4595 | 0.2194 |
| SK-BR-3 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1287 | 4168 | 0.3092 | -0.0525 |
| SK-BR-3 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1178 | 4168 | 0.2831 | -0.1043 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1103 | 4168 | 0.2643 | -0.1425 |
| SK-BR-3 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 984 | 4168 | 0.2361 | -0.2020 |