LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4604 | 4245 | 1.0849 | 1.1056 |
| SK-BR-3 | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4080 | 4245 | 0.9627 | 0.9542 |
| SK-BR-3 | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3632 | 4245 | 0.8563 | 0.8154 |
| SK-BR-3 | YM 201636 | 10 | uM | LJP5 | 72 | hr | 1401 | 1942 | 4245 | 0.4570 | 0.2231 |
| SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4829 | 4245 | 1.1428 | 1.1791 |
| SK-BR-3 | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4472 | 4245 | 1.0530 | 1.0654 |
| SK-BR-3 | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4448 | 4245 | 1.0482 | 1.0605 |
| SK-BR-3 | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4225 | 4245 | 0.9920 | 0.9857 |
| SK-BR-3 | TWS119 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3029 | 4245 | 0.7065 | 0.5855 |
| SK-BR-3 | TWS119 | 10 | uM | LJP5 | 72 | hr | 1401 | 1527 | 4245 | 0.3542 | 0.0283 |
| SK-BR-3 | PF477736 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1592 | 4245 | 0.3732 | 0.0754 |
| SK-BR-3 | PF477736 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1277 | 4245 | 0.2995 | -0.0623 |
| SK-BR-3 | PF477736 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1325 | 4245 | 0.3114 | -0.0384 |
| SK-BR-3 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1271 | 4245 | 0.2984 | -0.0641 |
| SK-BR-3 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1146 | 4245 | 0.2708 | -0.1186 |
| SK-BR-3 | PF477736 | 10 | uM | LJP5 | 72 | hr | 1401 | 1190 | 4245 | 0.2803 | -0.0998 |
| SK-BR-3 | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4952 | 4245 | 1.1690 | 1.2085 |
| SK-BR-3 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4081 | 4245 | 0.9574 | 0.9402 |
| SK-BR-3 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4428 | 4245 | 1.0447 | 1.0569 |
| SK-BR-3 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4146 | 4245 | 0.9745 | 0.9650 |
| SK-BR-3 | LDN-193189 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1026 | 4245 | 0.2352 | -0.2188 |
| SK-BR-3 | LDN-193189 | 10 | uM | LJP5 | 72 | hr | 1401 | 557 | 4245 | 0.1286 | -0.4568 |
| SK-BR-3 | PF431396 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4406 | 4245 | 1.0430 | 1.0574 |
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3284 | 4245 | 0.7780 | 0.7108 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 2164 | 4245 | 0.5112 | 0.3136 |