LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HG-5-88-01 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3097 | 4168 | 0.7436 | 0.6564 |
| SK-BR-3 | HG-5-88-01 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3487 | 4168 | 0.8366 | 0.7854 |
| SK-BR-3 | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3390 | 4168 | 0.8133 | 0.7538 |
| SK-BR-3 | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3503 | 4168 | 0.8403 | 0.7903 |
| SK-BR-3 | HG-5-88-01 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 3630 | 4168 | 0.8713 | 0.8325 |
| SK-BR-3 | HG-5-88-01 | 10 | uM | LJP6 | 72 | hr | 1401 | 2100 | 4168 | 0.5038 | 0.2930 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4507 | 4168 | 1.0819 | 1.1028 |
| SK-BR-3 | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3544 | 4168 | 0.8505 | 0.8041 |
| SK-BR-3 | HG-6-64-01 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3319 | 4168 | 0.7952 | 0.7259 |
| SK-BR-3 | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3136 | 4168 | 0.7525 | 0.6690 |
| SK-BR-3 | HG-6-64-01 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 2258 | 4168 | 0.5420 | 0.3530 |
| SK-BR-3 | HG-6-64-01 | 10 | uM | LJP6 | 72 | hr | 1401 | 516 | 4168 | 0.1238 | -0.4732 |
| SK-BR-3 | Neratinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1538 | 4245 | 0.3627 | 0.0579 |
| SK-BR-3 | Neratinib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1511 | 4245 | 0.3564 | 0.0471 |
| SK-BR-3 | Neratinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1408 | 4245 | 0.3327 | 0.0029 |
| SK-BR-3 | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1481 | 4245 | 0.3500 | 0.0349 |
| SK-BR-3 | Neratinib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1415 | 4245 | 0.3352 | 0.0069 |
| SK-BR-3 | Neratinib | 10 | uM | LJP5 | 72 | hr | 1401 | 1344 | 4245 | 0.3169 | -0.0282 |
| SK-BR-3 | JW-7-24-1 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3052 | 4168 | 0.7319 | 0.6391 |
| SK-BR-3 | JW-7-24-1 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3356 | 4168 | 0.8056 | 0.7434 |
| SK-BR-3 | JW-7-24-1 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3069 | 4168 | 0.7360 | 0.6451 |
| SK-BR-3 | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 2594 | 4168 | 0.6217 | 0.4773 |
| SK-BR-3 | JW-7-24-1 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 2131 | 4168 | 0.5111 | 0.3046 |
| SK-BR-3 | JW-7-24-1 | 10 | uM | LJP6 | 72 | hr | 1401 | 1209 | 4168 | 0.2900 | -0.0903 |
| SK-BR-3 | Dasatinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4423 | 4245 | 1.0445 | 1.0575 |