LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1775 | 4168 | 0.4253 | 0.1599 |
| SK-BR-3 | QL-X-138 | 10 | uM | LJP6 | 72 | hr | 1401 | 1228 | 4168 | 0.2947 | -0.0808 |
| SK-BR-3 | QL-XII-47 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2706 | 4168 | 0.6492 | 0.5192 |
| SK-BR-3 | QL-XII-47 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 2306 | 4168 | 0.5537 | 0.3728 |
| SK-BR-3 | QL-XII-47 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 2085 | 4168 | 0.5005 | 0.2878 |
| SK-BR-3 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1523 | 4168 | 0.3660 | 0.0548 |
| SK-BR-3 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1266 | 4168 | 0.3036 | -0.0639 |
| SK-BR-3 | QL-XII-47 | 10 | uM | LJP6 | 72 | hr | 1401 | 1099 | 4168 | 0.2636 | -0.1439 |
| SK-BR-3 | Torin1 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1894 | 4168 | 0.4545 | 0.2111 |
| SK-BR-3 | Torin1 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1724 | 4168 | 0.4137 | 0.1409 |
| SK-BR-3 | Torin1 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1536 | 4168 | 0.3687 | 0.0601 |
| SK-BR-3 | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1512 | 4168 | 0.3631 | 0.0499 |
| SK-BR-3 | Torin1 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1400 | 4168 | 0.3357 | -0.0014 |
| SK-BR-3 | Torin1 | 10 | uM | LJP6 | 72 | hr | 1401 | 1306 | 4168 | 0.3138 | -0.0436 |
| SK-BR-3 | Torin2 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1283 | 4245 | 0.3016 | -0.0579 |
| SK-BR-3 | Torin2 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1310 | 4245 | 0.3094 | -0.0423 |
| SK-BR-3 | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1242 | 4245 | 0.2925 | -0.0758 |
| SK-BR-3 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1188 | 4245 | 0.2807 | -0.0984 |
| SK-BR-3 | Torin2 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1064 | 4245 | 0.2511 | -0.1593 |
| SK-BR-3 | Torin2 | 10 | uM | LJP5 | 72 | hr | 1401 | 1047 | 4245 | 0.2457 | -0.1714 |
| SK-BR-3 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2442 | 4168 | 0.5864 | 0.4243 |
| SK-BR-3 | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 2521 | 4168 | 0.6054 | 0.4533 |
| SK-BR-3 | WZ-4-145 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 2283 | 4168 | 0.5477 | 0.3638 |
| SK-BR-3 | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 2084 | 4168 | 0.4995 | 0.2849 |
| SK-BR-3 | WZ-4-145 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1764 | 4168 | 0.4229 | 0.1560 |