LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | WZ-4-145 | 10 | uM | LJP6 | 72 | hr | 1401 | 1095 | 4168 | 0.2627 | -0.1454 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 905 | 4245 | 0.2133 | -0.2413 |
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 871 | 4245 | 0.2055 | -0.2592 |
| SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1023 | 4245 | 0.2423 | -0.1784 |
| SK-BR-3 | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 945 | 4245 | 0.2231 | -0.2192 |
| SK-BR-3 | WZ3105 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 957 | 4245 | 0.2251 | -0.2150 |
| SK-BR-3 | WZ3105 | 10 | uM | LJP5 | 72 | hr | 1401 | 992 | 4245 | 0.2328 | -0.1990 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3750 | 4168 | 0.9000 | 0.8707 |
| SK-BR-3 | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3519 | 4168 | 0.8450 | 0.7969 |
| SK-BR-3 | XMD11-50 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3374 | 4168 | 0.8095 | 0.7483 |
| SK-BR-3 | XMD11-50 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3196 | 4168 | 0.7664 | 0.6883 |
| SK-BR-3 | XMD11-50 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 2775 | 4168 | 0.6656 | 0.5437 |
| SK-BR-3 | XMD11-50 | 10 | uM | LJP6 | 72 | hr | 1401 | 1955 | 4168 | 0.4695 | 0.2358 |
| SK-BR-3 | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3250 | 4168 | 0.7797 | 0.7069 |
| SK-BR-3 | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3561 | 4168 | 0.8548 | 0.8103 |
| SK-BR-3 | XMD11-85h | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3737 | 4168 | 0.8966 | 0.8657 |
| SK-BR-3 | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3704 | 4168 | 0.8887 | 0.8554 |
| SK-BR-3 | XMD11-85h | 3.33 | uM | LJP6 | 72 | hr | 1401 | 3772 | 4168 | 0.9055 | 0.8773 |
| SK-BR-3 | XMD11-85h | 10 | uM | LJP6 | 72 | hr | 1401 | 3243 | 4168 | 0.7784 | 0.7055 |
| SK-BR-3 | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1628 | 4245 | 0.3857 | 0.1000 |
| SK-BR-3 | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1590 | 4245 | 0.3774 | 0.0848 |
| SK-BR-3 | XMD16-144 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1585 | 4245 | 0.3759 | 0.0824 |
| SK-BR-3 | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1666 | 4245 | 0.3951 | 0.1168 |
| SK-BR-3 | XMD16-144 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1623 | 4245 | 0.3851 | 0.0984 |
| SK-BR-3 | XMD16-144 | 10 | uM | LJP5 | 72 | hr | 1401 | 1171 | 4245 | 0.2773 | -0.1057 |